Results 101 to 110 of about 21,077 (297)

Creep Characteristics of Layered Rock Masses after Water Absorption Due to Structural Effects. [PDF]

Int J Environ Res Public Health, 2023
Xu H, Sun X, Zhang Y, Zhao C, Miao C, Wang D.   +5 more
europepmc   +1 more source

Creep Deformation Characteristics of Weathered Granite [PDF]

, 1977
Creep deformation characteristics of weathered granite were studied. While displacement of a structure on foundation rock is the main concern of foundation designers, the mechanical and especially the time dependent properties of weathered granite, which
OHNISHI, Yuzo, ADACHI, Toshihisa, YAMAMOTO, Kazuo, AKAI, Koichi   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Accelerated Creep of Asphalt Concrete at Medium Temperatures

Applied Sciences
In this paper, the accelerated creep under uniaxial tension of hot fine-grained dense asphalt concrete at temperatures of 22–24 °C and stresses from 0.084 MPa to 0.596 MPa is experimentally investigated.
Alibay Iskakbayev, Bagdat Teltayev, Yerbol Aitbayev, Azamat Zhaisanbayev   +3 more
doaj   +1 more source

Experimental study on uniaxial creep characteristics of sandstone with pre-peak unloading damage. [PDF]

Sci Rep, 2022
Liang Z, Ji P, Zhang Y, Qin N, Huang Q, Yu Z.   +5 more
europepmc   +1 more source

Creep Rate and Creep Model of Rockfill

, 2012
Due to the test duration restriction, not only the creep strain but also the creep rate should be considered to establish the creep model of the rockfill.
Yinqi, ZHANG, Haifanga, LI
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Experimental and Numerical Study on the Effect of Creep Behavior on Epoxy Composites Reinforced with Yttrium Oxide Powder

, 2020
The creep test is one of the important approaches to determining some mechanical properties of composite materials. This study was carried out to investigate the creep behaviour of an epoxy composite material that was reinforced with Y 2 O 3 powder at ...
Battawi, A. A., B.H. Abed, K.J. Jadee, A.A. Battawi, Jadee, K. J., Abed, B. H.   +5 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source