Results 121 to 130 of about 6,107 (297)

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee   +10 more
wiley   +1 more source

Determination of Creep Compliance and Tensile Strength of Hot-Mix Asphalt for Wearing Courses in Missouri

open access: yes, 2008
Creep compliance and indirect tensile (IDT) strength of hot-mix asphalt (HMA) are the two primary inputs to the low-temperature or thermal cracking module in the new Mechanistic-Empirical Pavement Design Guide (M-E PDG) software.
Lusher, S. M., Richardson, David Newton
core  

Concrete Creep Prediction Based on Improved Machine Learning and Game Theory: Modeling and Analysis Methods

open access: yesBuildings
Understanding the impact of creep on the long-term mechanical features of concrete is crucial, and constructing an accurate prediction model is the key to exploring the development of concrete creep under long-term loads.
Wenchao Li, Houmin Li, Cai Liu, Kai Min
doaj   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni   +7 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess   +3 more
wiley   +1 more source

Creep and creep rupture of laminated graphite/epoxy composites

open access: yes, 1981
An incremental numerical procedure based on lamination theory is developed to predict creep and creep rupture of general laminates. Existing unidirectional creep compliance and delayed failure data is used to develop analytical models for lamina response.
Morris, D. H.   +2 more
core  

Tensile creep and deformation modeling of vinyl ester polymer and its nanocomposite

open access: yes, 2009
This article discusses tensile creep behavior of vinyl ester polymer and its nanocomposite with 0.5 wt% functionalized carbon nanofibers. It is shown that for a constant temperature the creep resistance decreases with increasing stress.
Fatemi, A., Plaseied, A.
core   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

open access: yesAdvanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang   +7 more
wiley   +1 more source

Interconversion of dynamic modulus to creep compliance and relaxation modulus : numerical modeling and laboratory validation - final report. [PDF]

open access: yes
456-438Viscoelastic material functions such as time domain functions, such as, relaxation modulus and creep compliance,or frequency domain function, such as, complex modulus can be used to characterize the linear viscoelastic behaviorof asphalt concrete ...
Tarefder, Rafiqul A.   +2 more
core  

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