Results 51 to 60 of about 23,863,179 (302)

A Creep Model of Asphalt Mixture Based on Variable Order Fractional Derivative

open access: yesApplied Sciences, 2020
In order to quantitatively describe the time-varying mechanical properties of asphalt mixture during creep process, a nonlinear viscoelastoplastic creep model was proposed, by using variable-order fractional calculus.
W. Luo   +4 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Remnant creep based visco-elastic model for concrete creep analysis [PDF]

open access: yesProceedings of the Institution of Civil Engineers - Structures and Buildings, 2015
Creep of concrete could cause adverse stress redistributions and excessive deformations. Its structural effects can be assessed by conducting time-step analysis using finite-element methods with time-integration formulation, in which the creep strain at any time is determined as the cumulative creep responses to stress increments in previous time ...
Kwan, AKH, Ng, PL
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Investigation of an Empirical Creep Constitutive Model of Changsha Red Loam

open access: yesBuildings, 2023
To describe and predict the creep deformation of Changsha red loam (including sandy soil and silty clay) in China, an empirical creep model was proposed based on a laboratory consolidation compression test. Two classical soil layers were sampled from the
Lin Long, Zhida Li, Yunyu Li
doaj   +1 more source

Application of an advanced mean-field dislocation creep model to P91 for calculation of creep curves and time-to-rupture diagrams

open access: yes, 2020
This work deals with the development of a comprehensive mean-field dislocation creep model and its application to the martensitic 9% Cr-steel P91. Microstructural data from literature, EBSD measurements and results from precipitate kinetic simulations ...
F. Riedlsperger   +6 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research on Unsteady Burgers Creep Constitutive Model and Secondary Development Application

open access: yesApplied Sciences
Considering the complexity and diversity of water-rich soft soil strata, indoor triaxial shear tests and creep tests were conducted on soft soil to explore its deformation law and creep characteristics.
Ruonan Zhu   +4 more
doaj   +1 more source

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