Results 31 to 40 of about 31,159 (180)

The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function

Cell Reports, 2020
Summary: Exposure to natural metabolites contributes to the risk of cardiometabolic diseases (CMDs). Through metabolome profiling, we identify the inverse correlation between serum concentrations of 4-cresol and type 2 diabetes.
Francois Brial, Fawaz Alzaid, Kazuhiro Sonomura, Yoichiro Kamatani, Kelly Meneyrol, Aurélie Le Lay, Noémie Péan, Lyamine Hedjazi, Taka-Aki Sato, Nicolas Venteclef, Christophe Magnan, Mark Lathrop, Marc-Emmanuel Dumas, Fumihiko Matsuda, Pierre Zalloua, Dominique Gauguier   +15 more
doaj   +1 more source

Evaluation of biodegradation kinetic constants for aromatic compounds by means of aerobic batch experiments [PDF]

, 2006
Kinetics of aerobic biodegradation have been investigated for twenty aromatic species using sludges collected from the aeration basin of municipal sewage treatment plants. The reproducibility of the results is tested with respect to the sludges period of
ANDREOZZI, ROBERTO, CESARO, RAFFAELE, MAROTTA, RAFFAELE, PIROZZI, FRANCESCO   +3 more
core   +1 more source

Effective p-cresol removal through catalytic liquid-phase oxidation under moderate conditions using Pt/CeO2-ZrO2-SnO2/SBA-16 as a catalyst

Journal of Asian Ceramic Societies, 2020
Cresol is among the phenolic compounds that are frequently found in industrial wastewater streams. Most notably, p-cresol has the highest toxicity and the highest permeability effect on skin of all the cresol isomers; hence, wastewater treatment for p ...
Abdul Rohman Supandi, Naoyoshi Nunotani, Nobuhito Imanaka   +2 more
doaj   +1 more source

Probiotic Bifidobacteria Mitigate the Deleterious Effects of para-Cresol in a Drosophila melanogaster Toxicity Model

mSphere, 2022
Renal impairment associated with chronic kidney disease (CKD) causes the buildup of uremic toxins that are deleterious to patient health. Current therapies that manage toxin accumulation in CKD offer an incomplete therapeutic effect against toxins such ...
Gerrit A. Stuivenberg, John A. Chmiel, Polycronis P. Akouris, Jeremy P. Burton, Gregor Reid   +4 more
doaj   +1 more source

Ionization effects on the partitioning behavior of food and beverage aroma compounds between aqueous phases and air and organic matrices [PDF]

, 2011
Aroma compounds in the Flavornet database were screened for ionizable functional groups such as carboxylic acids, aliphatic and aromatic amines, phenols, alcohols, and thiols.
Kaya Forest, Sierra Rayne
core   +2 more sources

Serum Concentration of p-Cresol and Indoxyl Sulfate in Elderly Hemodialysis Patients

International Journal of Gerontology, 2011
Background: Uremic syndrome is a consequence of the retention of uremic solutes. Indoxyl sulfate (IS) and para-cresol (p-cresol) belong to the group of protein-bound uremic toxins that are poorly cleared by dialysis and are associated with poor clinical ...
Cheng-Jui Lin, Chih-Jen Wu, Chi-Feng Pan, Yi-Chou Chen, Fang-Ju Sun, Han-Hsiang Chen   +5 more
doaj   +1 more source

Isolation and characterization of Alicycliphilus denitrificans strain BC, which grows on benzene with chlorate as the electron acceptor [PDF]

, 2008
A bacterium, strain BC, was isolated from a benzene-degrading chlorate-reducing enrichment culture. Strain BC degrades benzene in conjunction with chlorate reduction.
Broeke, H., ten, Doesburg, W.C.J., van, Gerritse, J., Junca, H., Kieboom, C., van den, Langenhoff, A.A.M., Stams, A.J.M., Tan, N.C.G., Weelink, S.A.B.   +8 more
core   +2 more sources

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Unexpected transformation of dissolved phenols to toxic dicarbonyls by hydroxyl radicals and UV light. [PDF]

, 2018
Water treatment systems frequently use strong oxidants or UV light to degrade chemicals that pose human health risks. Unfortunately, these treatments can result in the unintended transformation of organic contaminants into toxic products.
Ford, Breanna, Nomura, Daniel K, Prasse, Carsten, Sedlak, David L   +3 more
core   +1 more source

Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p‐cresol Formation

Advanced Science, EarlyView.
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang, Yifeng Wei, Xumei Liu, Dazhi Liu, Zhenyu Liu, Yang Tong, Jinyu Yin, Ankanahalli N. Nanjaraj Urs, Meining Xing, Mark A. Harrison, Chuyuan Zhang, Sheng Yang, Yunzi Luo, Ee Lui Ang, Huimin Zhao, Yan Zhang   +15 more
wiley   +1 more source