Results 61 to 70 of about 5,030,757 (219)
Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease [PDF]
Several molecular subtypes of sporadic Creutzfeldt-Jakob disease have been identified and electroencephalogram and cerebrospinal fluid biomarkers have been reported to support clinical diagnosis but with variable utility according to subtype.
Summers, DM +95 more
core +3 more sources
We examined changes in perceived risks associated with chronic wasting disease (CWD) and perceived trust in wildlife agencies over time across 10 studies in eight states. Results indicated that perceived risks to both deer and humans declined the longer the disease had been in a state. Results also indicated that agency trust evaluations were positive,
Jerry J. Vaske, Craig A. Miller
wiley +1 more source
Variant Creutzfeldt-Jakob disease in the United Kingdom
The Department of Health in England has issued the latest figures on known cases of Creutzfeldt-Jakob disease in the United Kingdom (UK), including cases of variant Creutzfeldt-Jakob disease (vCJD), the form of the disease thought to be linked to bovine ...
E Hoile
core +3 more sources
Human brain matters: Navigating the neuropathology of COVID‐19
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland +4 more
wiley +1 more source
Movement Disorders in Prionopathies: A Systematic Review
Background: Movement disorders are frequent features of prionopathies. However, their prevalence and onset remain poorly described. Methods: We performed a systematic review of case reports and case series of pathologically- and genetically confirmed ...
Federico Rodriguez-Porcel +11 more
doaj +1 more source
Motives and barriers to blood donation among adults aged over 50 years: A qualitative analysis
Abstract Background Ageing populations will increase demand for blood‐products and donors who supply them. While blood collection agencies (BCAs) typically target younger people to expand supply, recruiting donors aged 50+ is also a potential solution. However, few studies focus exclusively on this group.
Melissa K. Hyde +6 more
wiley +1 more source
The Exceptions to the Central Dogma of Biology—Bending the Rules and Extending the Scope
ABSTRACT The central dogma is an organizing framework for how information flows in biological systems. First presented in 1957 by Francis Crick in his talk “On Protein Synthesis” as a fundamental hypothesis of how information is transferred from DNA to proteins but not out of proteins, it is now introduced in cell biology textbooks as three sequential ...
Anat Ben‐Zvi
wiley +1 more source
Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven +16 more
wiley +1 more source
Changes in serum β‐synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome
Abstract INTRODUCTION There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood biomarkers ...
Alba Cervantes González +23 more
wiley +1 more source
The Molecular Pathology of Prion Diseases [PDF]
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Vassallo, Neville +2 more
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