Results 241 to 250 of about 164,927 (267)
Some of the next articles are maybe not open access.
Acta Endocrinologica, 1984
Abstract. The biological activity of ovine (o) and human (h) corticotrophin releasing factor (CRF) in normal volunteers was investigated. Nine subjects received an iv bolus injection of 50, 100 and 200 μg oCRF. There was no dose-response relationship between the injected oCRF dosage and stimulated ACTH, β-endorphin, and cortisol secretion. The addition
G K, Stalla +3 more
openaire +2 more sources
Abstract. The biological activity of ovine (o) and human (h) corticotrophin releasing factor (CRF) in normal volunteers was investigated. Nine subjects received an iv bolus injection of 50, 100 and 200 μg oCRF. There was no dose-response relationship between the injected oCRF dosage and stimulated ACTH, β-endorphin, and cortisol secretion. The addition
G K, Stalla +3 more
openaire +2 more sources
CRF antagonist partially reverses CRF- and stress-induced effects on feeding
Brain Research Bulletin, 1986Exogenous corticotropin releasing factor (CRF) causes centrally mediated behavioral changes including decreased feeding and increased grooming. These behavioral changes are also seen in response to some stressors. However, the role of endogenous CRF in the behavioral response to stressors has not been investigated fully. We report below our findings on
D D, Krahn +3 more
openaire +2 more sources
CRF and CRF Receptors: Role in Stress Responsivity and Other Behaviors
Annual Review of Pharmacology and Toxicology, 2004Since corticotropin-releasing factor (CRF) was first characterized, a growing family of ligands and receptors has evolved. The mammalian family members include CRF, urocortinI (UcnI), UcnII, and UcnIII, along with two receptors, CRFR1 and CRFR2, and a CRF binding protein.
Tracy L, Bale, Wylie W, Vale
openaire +2 more sources
2017
Chapter 5 explains how excessive fear is tied to anxiety disorders, and vulnerability to the breakdown of mental and physical health. CRF in the brain is tied to these events. CRF, for instance, may be constrained by the neurotransmitter GABA in key regions of the forebrain and is mobilized by brainstem catecholaminergic neurons that are critical in ...
openaire +1 more source
Chapter 5 explains how excessive fear is tied to anxiety disorders, and vulnerability to the breakdown of mental and physical health. CRF in the brain is tied to these events. CRF, for instance, may be constrained by the neurotransmitter GABA in key regions of the forebrain and is mobilized by brainstem catecholaminergic neurons that are critical in ...
openaire +1 more source
Current opinion in investigational drugs (London, England : 2000), 2001
DuPont (formerly DuPont Merck), Neurocrine Biosciences and Cephalon are conducting a joint investigation into corticotropin releasingfactor (CRF) ligands. These compounds may have potential as antidepressants and anxiolytics. SV-030 and other analogs from the series are entering preclinical development [361291], [362064].
openaire +3 more sources
DuPont (formerly DuPont Merck), Neurocrine Biosciences and Cephalon are conducting a joint investigation into corticotropin releasingfactor (CRF) ligands. These compounds may have potential as antidepressants and anxiolytics. SV-030 and other analogs from the series are entering preclinical development [361291], [362064].
openaire +3 more sources
CRF and CRF-related peptides in stress adaptation: From invertebrates to man
General and Comparative Endocrinology, 2007Contains fulltext : 35048.pdf (Publisher’s version ) (Closed access)
openaire +3 more sources