Results 91 to 100 of about 48,713 (266)

Untersuchung des CRH/CRH-Rezeptor Systems mit Hilfe Zelltyp-spezifisch CRH-überexprimierender Mauslinien.

open access: yes, 2010
Das Neuropeptid Corticotropin-Releasing-Hormone (CRH) spielt sowohl als Hormon als auch als Neuromodulator eine wichtige Rolle im Rahmen der physiologischen Stressantwort.
Ableitner, M.
core  

The hypothalamic-pituitary-adrenal axis in critical illness [PDF]

open access: yes, 1993
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Winkelmann, W.   +3 more
core  

Proliferative response of Crh+/+ and Crh−/− fibroblasts.

open access: yes, 2013
(a) Fibroblasts isolated from Crh+/+ and Crh−/− dermis plated at an initial density of 8×103 cells/well for four days.
Maria Venihaki (348138)   +8 more
core   +1 more source

A guide to host genetic determinants of female microbiome composition across distinct anatomical niches

open access: yesThe FEBS Journal, EarlyView.
Host genetic variation in immune regulation and cell signalling genes was associated with microbiome composition across vaginal, gut, oral and skin sites, while associations involving metabolic function, epithelial barrier integrity and hormonal processes were more site‐specific. Overall, our findings indicate that host genetic variation contributes to
Isabella Margaret Davidson   +4 more
wiley   +1 more source

Η μελέτη της έκφρασης των υποδοχέων της CRH, CRH-R1 και CRH-R2 σε βλαστοκύστεις ποντικών

open access: yes, 2017
Η CRH (Corticotropin-realising hormone, κορτικοεκλιτίνη) είναι μια πεπτιδική ορμόνη, η οποία παράγεται από τον παρακοιλιακό πυρήνα του υποθαλάμου και στη συνέχεια μεταφέρεται στον πρόσθιο λοβό της υπόφυσης, μέσω του πυλαίου αγγειακού συστήματος,
Κουβουτσάκη Κωνσταντίνα   +1 more
core  

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner   +59 more
wiley   +1 more source

Genetische Analyse CRH-modulierter Stress-Netzwerke

open access: yes, 2016
Dysregulated corticotropin-releasing hormone (CRH)-circuits have been implicated in the pathophysiology of stress-related psychiatric disorders. This study provides novel insights into the underlying CRH-neurotransmitter interactions.
Dedic, Nina
core  

Patient Preferences for the Treatment of Haemophilia A and B in France

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Haemophilia impacts health and quality of life. Advances in treatments such as factor replacement therapy (FRT), bispecific monoclonal antibody (BS‐mAb), gene therapy (GT), rebalancing treatment and high sustained factor necessitate understanding patient preferences to inform therapeutic strategies. Aim This study quantified trade‐
Yesim Dargaud   +10 more
wiley   +1 more source

Lipocortin-1 inhibits CRH stimulation of plasma ACTH and IL-1 beta-stimulated hypothalamic CRH release in rats.

open access: yes, 1996
A 188-amino acid NH2-terminal fragment of recombinant human lipocortin-1 (rhLC-1) (LC-1 fragment) mimics glucocorticoid (and rhLC-1) inhibition of corticotrophin-releasing hormone (CRH)-stimulated release of adrenocorticotrophin (ACTH) from rat anterior ...
Carey, F   +7 more
core   +1 more source

A Common Language for the Multidisciplinary Team: Point‐of‐Care Musculoskeletal Ultrasound in Modern Haemophilia Care

open access: yesHaemophilia, EarlyView.
ABSTRACT The evolving haemophilia care landscape has evolved with personalised prophylaxis, new coagulation factor molecules, non‐replacement therapies, and gene therapy, leading to significantly reduced bleeding frequency and haemophilic arthropathy burden.
Hortensia De la Corte‐Rodriguez   +16 more
wiley   +1 more source

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