Results 101 to 110 of about 83,953 (231)

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl   +10 more
wiley   +1 more source

Advancing Emergency Nursing Care Through International Collaboration and Behaviour Change Theory

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim In this paper, the development of an evidence‐informed, data‐driven strategy for implementation of the HIRAID emergency nursing framework in Thailand is reported. HIRAID stands for History including Infection risk, Red flags, Assessment, Interventions, Diagnostics, reassessment and communication.
Julie Considine   +8 more
wiley   +1 more source

The effect of 'Astressin', a novel antagonist of corticotropin releasing hormone (CRH), on CRH-induced seizures in the infant rat: comparison with two other antagonists. [PDF]

open access: yes, 1996
Corticotropin releasing hormone (CRH) has both neuroendocrine effects, promoting ACTH release from the anterior pituitary, and neurotransmitter properties, acting on specific neuronal populations.
Baram, TZ   +3 more
core   +1 more source

Practitioner Review: Infant mental health meets cell and molecular biology – a look to the future

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background A major research effort in the past two decades has begun to illuminate how experience ‘gets under the skin’ – that is – the cellular and molecular processes that are associated with adversity and resilience. Methods We selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory
Charles H. Zeanah   +3 more
wiley   +1 more source

Efficacy of Online Training for Improving Camp Staff Competency

open access: yes, 2018
Preparing competent staff is a critical issue within the camp community. This quasi-experimental study examined the effectiveness of an online course for improving staff competency in camp healthcare practices among college-aged camp staff and a ...
Alice M. Brawley   +22 more
core   +1 more source

CRH-Like Peptides in Human Reproduction

open access: yesCurrent Medicinal Chemistry, 2009
CRH and Urocortins 1, 2 and 3 comprise the, so far identified, members of the CRH family of peptides in humans. Their actions are mediated through two distinct receptors, CRHR1 and CRHR2, encoded by different genes.
Zoumakis, E.   +2 more
openaire   +4 more sources

A mini‐review of chronic suppression of the hypothalamic–pituitary–adrenal axis in animals with P‐glycoprotein deficiency

open access: yesJournal of Small Animal Practice, EarlyView.
This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza   +4 more
wiley   +1 more source

Effect of Soluble Epoxide Hydrolase on the Modulation of Coronary Reactive Hyperemia: Role of Oxylipins and PPARγ.

open access: yesPLoS ONE, 2016
Coronary reactive hyperemia (CRH) is a physiological response to ischemic insult that prevents the potential harm associated with an interruption of blood supply.
Ahmad Hanif   +4 more
doaj   +1 more source

Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up

open access: yesExperimental Physiology, EarlyView.
Abstract In patients previously hospitalised for COVID‐19, a 12‐week high‐intensity interval training (HIIT) intervention has previously been shown to increase left ventricular mass (LVM) immediately after the intervention. In the present study, we examined the effects of the same HIIT scheme on LVM, pulmonary diffusing capacity, symptom severity and ...
Iben Elmerdahl Rasmussen   +21 more
wiley   +1 more source

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