Results 111 to 120 of about 48,713 (266)
Intramuscular pathways of maladaptation in overtraining syndrome
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
Background Ectopic ACTH- and/or CRH-secreting pheochromocytomas (ACTH+CRH+PCCs) are rare tumors that can mimic Cushing’s syndrome and complicate the diagnosis and treatment clinically.
Wan Su +14 more
doaj +1 more source
IL-6 and TGF-β1 production from Crh+/+ and Crh−/− fibroblasts.
Primary dermal fibroblasts isolated from Crh+/+ and Crh−/− mice were cultured in 24-well plates (105 cells/well). Supernatants were collected and analyzed by ELISA for IL-6 (a) or TGF-β1 (b).
Maria Venihaki (348138) +8 more
core +1 more source
Healthcare Waste Generation Rates in the Three Categories of Public Healthcare Facilities in Malawi
Two tertiary (Kamuzu and Mzuzu Central), secondary (Nkhata Bay and Rumphi), and primary (Bolero and Chintheche Rural) healthcare institutions participated in a study on healthcare waste. Waste was categorized as nonhazardous or hazardous. Significant differences in waste generation rates were observed on the basis of facility type (p < 0.001). ABSTRACT
Grace O. Ogbonna +5 more
wiley +1 more source
Genetic dissection of CRH-controlled neurocircuitries of stress.
Dysregulated corticotropin-releasing hormone (CRH)-circuits have been implicated in the pathophysiology of stress-related psychiatric disorders. This study provides novel insights into the underlying CRH-neurotransmitter interactions.
Dedic, N.
core
Improving String Matching through Enhanced Hashing
ABSTRACT Background Hashing offers opportunities to tune string matching algorithms while enabling efficient data retrieval and pattern detection. Many of the best algorithms apply hashing. Objective We try to develop faster online algorithms for exact string matching.
Francesco Pio Marino, Jorma Tarhio
wiley +1 more source
Novel functional roles for CRH -binding protein at the pituitary.
Corticotropin-releasing hormone (CRH) is the key regulator of the mammalian stress response. The bioactivity of CRH and other CRH-like peptides is modulated by the CRH-binding protein (CRH-BP), a secreted glycoprotein that is expressed at multiple sites ...
Speert, Debra Beth
core
ABSTRACT Somatic mutations in the MAPK signaling pathway are frequently identified at AML diagnosis; however, their impact on treatment resistance and long‐term survival remains unclear. We conducted a retrospective study of patients with newly diagnosed MAPK‐mutated AML seen at the University of Iowa Health Care.
Kensuke Takaoka +6 more
wiley +1 more source
Dissecting the role of CRH and CRH-R1 in Alzheimer´s disease.
In Alzheimer´s Disesase (AD) alterations of the corticotropin-releasing hormone (CRH) system and a hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis have been reported. To shed light on the involvement of CRH and its receptor CRH-R1 in
Lerche, K.
core

