Results 11 to 20 of about 48,713 (266)

Reduced expression of CRH receptor type 1 in upper segment human myometrium during labour [PDF]

Reproductive Biology and Endocrinology, 2009
Background Corticotropin-releasing hormone (CRH) and CRH-related peptide are shown to modulate uterine contractility through two CRH receptor subtype, CRH-R1 and CRH-R2 during pregnancy.
Gao Lu, Zhang Lanmei, Cong Binhai, Ni Xin   +3 more
doaj   +2 more sources

Structural characterisation of a cyprinid (Cyprinus carpio L.) CRH, CRH-BP and CRH-R1, and the role of these proteins in the acute stress response [PDF]

Journal of Molecular Endocrinology, 2004
Abstract We elucidated the structure of the principle factors regulating the initiation of the acute stress response in common carp: corticotrophin-releasing hormone (CRH), CRH-receptor 1 (CRH-R1) and CRH-binding protein (CRH-BP). Phylogenetic analyses reveal that these proteins are evolutionarily well conserved in vertebrates.
Huising, M.O., Metz, J.R., van Schooten, C., Taverne-Thiele, J.J., Hermsen, G.J., Verburg-van Kemenade, B.M.L., Flik, G.   +6 more
openaire   +5 more sources

Differential CRH expression level determines efficiency of Cre- and Flp-dependent recombination [PDF]

Frontiers in Neuroscience, 2023
Corticotropin-releasing hormone expressing (CRH+) neurons are distributed throughout the brain and play a crucial role in shaping the stress responses.
Chen Zhao, Clemens Ries, Ying Du, Jingwei Zhang, Kenji Sakimura, Keiichi Itoi, Jan M. Deussing   +6 more
doaj   +2 more sources

A novel role of peripheral corticotropin-releasing hormone (CRH) on dermal fibroblasts. [PDF]

PLoS ONE, 2011
Corticotropin-releasing hormone, or factor, (CRH or CRF) exerts important biological effects in multiple peripheral tissues via paracrine/autocrine actions.
Olga Rassouli, George Liapakis, Iakovos Lazaridis, George Sakellaris, Kostas Gkountelias, Achille Gravanis, Andrew N Margioris, Katia P Karalis, Maria Venihaki   +8 more
doaj   +2 more sources

CRH Receptors in Human Reproduction

Current Molecular Pharmacology, 2018
Corticotropin releasing hormone (CRH), the main peptide-mediator of stress, has been found in the female reproductive system.Herein, the role of CRH receptors in the female reproductive system is presented.It is clear that CRH receptors are involved in the regulation of the hypothalamic-pituitaryovarian axis, while locally are associated with ...
Makrigiannakis, A., Vrekoussis, T., Zoumakis, E., Navrozoglou, I., Kalantaridou, S.N.   +4 more
openaire   +4 more sources

CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus

Cell Reports, 2019
Summary: Local cues in the adult neurogenic niches dynamically regulate homeostasis in neural stem cells, whereas their identity and associated molecular mechanisms remain poorly understood.
Yassemi Koutmani, Ioannis A. Gampierakis, Alexia Polissidis, Methodios Ximerakis, Paraskevi N. Koutsoudaki, Alexandros Polyzos, George Agrogiannis, Sevasti Karaliota, Dimitra Thomaidou, Lee L. Rubin, Panagiotis K. Politis, Katia P. Karalis   +11 more
doaj   +2 more sources

MOLECULAR EVOLUTION OF GPCRS: CRH/CRH receptors [PDF]

Journal of Molecular Endocrinology, 2014
Corticotrophin-releasing hormone (CRH) is the pivotal neuroendocrine peptide hormone associated with the regulation of the stress response in vertebrates. However, CRH-like peptides are also found in a number of invertebrate species. The origin of this peptide can be traced to a common ancestor of lineages leading to chordates and to arthropods ...
David A, Lovejoy, Belinda S W, Chang, Nathan R, Lovejoy, Jon, del Castillo   +3 more
openaire   +2 more sources

Μελέτη έκφρασης των υποδοχέων CRH-R1 και CRH-R2 της ορμόνης CRH σε ανθρώπινες βλαστοκύστεις

, 2018
CRH (Corticotrophin Releasing Hormone) is a 41 amino acid neuropeptide, firstly isolated from sheep hypothalamus. CRH is basicly implicated in the regulation of the secretion of ACTH (Adrenocorticotropic hormone) from pituitary gland and is widely dispersed in the brain, thus orchestrating endocrinological and behavioral Autonomous Nervous System (ANS)
Kasfiki Eleni Sofia, Κασφίκη Ελένη Σοφία   +1 more
openaire   +2 more sources

Differential Expression of CRH, UCN, CRHR1 and CRHR2 in Eutopic and Ectopic Endometrium of Women with Endometriosis. [PDF]

, 2013
Endometriosis is considered as a benign aseptic inflammatory disease, characterised by the presence of ectopic endometrium-like tissue. Its symptoms (mostly pain and infertility) are reported as constant stressors.
Sabatini, Luca, Aikaterini Vergetaki, Antonis Makrigiannakis, Vergetaki, Aikaterini, Jeschke, Udo, Taliouri, Eirini, Evangelia A Papakonstanti, Papakonstanti, Evangelia A., Udo Jeschke, Thomas Vrekoussis, Vrekoussis, Thomas, Eirini Taliouri, Luca Sabatini, Makrigiannakis, Antonis, Sabatini Luca, Papakonstanti Evangelia A., Makrigiannakis Antonis, Jeschke Udo, Taliouri Eirini, Vergetaki Aikaterini, Vrekoussis Thomas   +20 more
core   +2 more sources

The combined dexamethasone/CRH Test (DEX/CRH test) and prediction of acute treatment response in major depression. [PDF]

, 2009
In this study the predictive value of the combined dexamethasone/CRH test (DEX/CRH test) for acute antidepressant response was investigated. In 114 depressed inpatients suffering from unipolar or bipolar depression (sample 1) the DEX/CRH test was ...
Daniela Eser, Baghai Thomas C., Herrmann, Sascha, Rupprecht Rainer, Born, Christoph, Sascha Herrmann, Schüle Cornelius, Cornelius Schüle, Sibylle Häfner, Rupprecht, Rainer, Häfner Sibylle, Eser, Daniela, Schüle, Cornelius, Baghai, Thomas C., Herrmann Sascha, Christoph Born, Rainer Rupprecht, Thomas C. Baghai, Häfner, Sibylle, Thomas C Baghai, Eser Daniela, Born Christoph   +21 more
core   +1 more source