Results 71 to 80 of about 9,718,287 (381)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Crisis management, global challenges, and sustainable development from an Asian perspective
Asian Business & Management, 2020 Research on crisis management has accumulated a vast body of knowledge that has assisted us with comprehending complex business and management phenomena.
Yipeng Liu, F. Froese
semanticscholar +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
The Earthquake in Haiti: Law and Legal Issues in International Disaster Response
Московский журнал международного права, 2010 The catastrophic earthquake that devastated Haiti on January 12, 2010, drew aid from many countries and international organizations. However, despite rapid response of the world community, the large-scale relief operations were confronted by legal ...
A. A. Ilyushchenko
doaj +1 more source
How is EU cooperation on the Covid-19 crisis perceived in member states? CEPS Commentary 21 April [PDF]
, 2020 The crisis caused by the spread of Covid-19 has demonstrated how difficult European cooperation can be, especially in policy areas where the EU has only a legal competence to support member states.
Blockmans, Steven, Russack, Sophia
core
Crisis Management Process - A Literature Review and a Conceptual Integration
, 2020 The 21st-century business environment requires permanent crisis management. Nowadays, managers seek to deal with a potential crisis effectively, with minimum losses or to avert the potential crisis in the best case.
Veronika VaĹĄĂÄkovĂĄ
semanticscholar +1 more source
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Integration of investment strategies in the system of strategic planning of territorial development
Управление, 2019 The issues of legal regulation of investment activity at the level of the Federation entities of the Russian Federation have been considered. The purpose of the research is the study of strategic documents in the field of investment activities of the ...
O. V. Kozhevina
doaj +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source