Results 11 to 20 of about 1,216,536 (293)

CRISPR-Cas systems in multicellular cyanobacteria [PDF]

open access: yesRNA Biology, 2018
Novel CRISPR-Cas systems possess substantial potential for genome editing and manipulation of gene expression. The types and numbers of CRISPR-Cas systems vary substantially between different organisms. Some filamentous cyanobacteria harbor > 40 different putative CRISPR repeat-spacer cassettes, while the number of cas gene instances is much lower ...
Shengwei Hou   +6 more
openaire   +5 more sources

Application of CRISPR/Cas Systems in the Nucleic Acid Detection of Infectious Diseases

open access: yesDiagnostics, 2022
The CRISPR/Cas system is a protective adaptive immune system against attacks from foreign mobile genetic elements. Since the discovery of the excellent target-specific sequence recognition ability of the CRISPR/Cas system, the CRISPR/Cas system has shown
Junwei Li   +8 more
doaj   +1 more source

Analysis of genetic structure and function of clustered regularly interspaced short palindromic repeats loci in 110 Enterococcus strains

open access: yesFrontiers in Microbiology, 2023
Clustered regularly interspaced short palindromic repeats (CRISPR) and their CRISPR-associated proteins (Cas) are an adaptive immune system involved in specific defenses against the invasion of foreign mobile genetic elements, such as plasmids and phages.
Shuan Tao   +9 more
doaj   +1 more source

CRISPR-Cas systems feature and targeting phages diversity in Lacticaseibacillus rhamnosus strains

open access: yesFrontiers in Microbiology, 2023
One of the most important adaptive immune systems in bacteria against phages is clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (CAS) genes.
Bahman Panahi   +2 more
doaj   +1 more source

Structural studies of CRISPR-associated proteins [PDF]

open access: yes, 2013
Clustered regularly interspaced short palindromic repeats (CRISPRs) act to prevent viral infection and horizontal gene transfer in prokaryotes. The genomic CRISPR array contains short sequences (“spacers”) that are derived from foreign genetic elements ...
Reeks, Judith
core   +2 more sources

Recent Advances in CRISPR/Cas-Based Biosensors for Protein Detection

open access: yesBioengineering, 2022
CRISPR is an acquired immune system found in prokaryotes that can accurately recognize and cleave foreign nucleic acids, and has been widely explored for gene editing and biosensing.
Jing Wang   +3 more
doaj   +1 more source

CRISPR-Cas Systems in Streptococci [PDF]

open access: yesCurrent Issues in Molecular Biology, 2019
Streptococci are one of the most important and common constituents of the host's microbiota and can colonize and live in the upper respiratory and urogenital tract of humans and animals. The CRISPR-Cas systems (i.e., clustered regularly interspaced short palindromic repeat, with CRISPR-associated proteins) found in bacteria and archaea provide sequence-
Tao, Gong   +7 more
openaire   +2 more sources

Viral Diversity Threshold for Adaptive Immunity in Prokaryotes

open access: yesmBio, 2012
Bacteria and archaea face continual onslaughts of rapidly diversifying viruses and plasmids. Many prokaryotes maintain adaptive immune systems known as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (Cas ...
Ariel D. Weinberger   +4 more
doaj   +1 more source

Application of different types of CRISPR/Cas-based systems in bacteria

open access: yesMicrobial Cell Factories, 2020
As important genome editing tools, CRISPR/Cas systems, especially those based on type II Cas9 and type V Cas12a, are widely used in genetic and metabolic engineering of bacteria.
Zhenquan Liu   +4 more
doaj   +1 more source

A global comprehensive study of the distribution of type I-E and type I-E* CRISPR-Cas systems in Klebsiella pneumoniae

open access: yesIndian Journal of Community Medicine, 2023
Background: The CRISPR-Cas (clustered regularly interspaced short palindromic repeats–CRISPR-associated proteins) systems are the short DNA sequences and RNA-dependent nuclease involved in the adaptive immunity in bacteria and archaea. The type of CRISPR-
Anand Babu Kannadasan   +2 more
doaj   +1 more source

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