Results 11 to 20 of about 80,955 (297)
Viral Diversity Threshold for Adaptive Immunity in Prokaryotes [PDF]
mBio, 2012 Bacteria and archaea face continual onslaughts of rapidly diversifying viruses and plasmids. Many prokaryotes maintain adaptive immune systems known as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (Cas ...
Ariel D. Weinberger +4 more
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Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium. [PDF]
PLoS ONE, 2015 CRISPR-Cas systems constitute adaptive immune systems for antiviral defense in bacteria. We investigated the occurrence and diversity of CRISPR-Cas systems in 48 Bifidobacterium genomes to gain insights into the diversity and co-evolution of CRISPR-Cas ...
Alexandra E Briner +9 more
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CRISPR-Cas Systems in Prokaryotes [PDF]
Polish Journal of Microbiology, 2015 Prokaryotic organisms possess numerous strategies that enable survival in hostile conditions. Among others, these conditions include the invasion of foreign nucleic acids such as bacteriophages and plasmids. The clustered regularly interspaced palindromic repeats-CRISPR-associated proteins (CRISPR-Cas) system provides the majority of bacteria and ...
Burmistrz, Michał, Pyrć, Krzysztof
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Microbiology Spectrum, 2022 Acinetobacter baumannii is a well-known human opportunistic pathogen in nosocomial infections, and the emergence of multidrug-resistant Acinetobacter baumannii has become a complex problem for clinical anti-infective treatments.
Yuhang Wang +8 more
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Application of CRISPR/Cas Systems in the Nucleic Acid Detection of Infectious Diseases
Diagnostics, 2022 The CRISPR/Cas system is a protective adaptive immune system against attacks from foreign mobile genetic elements. Since the discovery of the excellent target-specific sequence recognition ability of the CRISPR/Cas system, the CRISPR/Cas system has shown
Junwei Li +8 more
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Frontiers in Microbiology, 2023 Clustered regularly interspaced short palindromic repeats (CRISPR) and their CRISPR-associated proteins (Cas) are an adaptive immune system involved in specific defenses against the invasion of foreign mobile genetic elements, such as plasmids and phages.
Shuan Tao +9 more
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CRISPR-Cas systems feature and targeting phages diversity in Lacticaseibacillus rhamnosus strains
Frontiers in Microbiology, 2023 One of the most important adaptive immune systems in bacteria against phages is clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (CAS) genes.
Bahman Panahi +2 more
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Recent Advances in CRISPR/Cas-Based Biosensors for Protein Detection
Bioengineering, 2022 CRISPR is an acquired immune system found in prokaryotes that can accurately recognize and cleave foreign nucleic acids, and has been widely explored for gene editing and biosensing.
Jing Wang +3 more
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CRISPR-Cas Controls Cryptic Prophages [PDF]
International Journal of Molecular Sciences, 2021 The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages.
Sooyeon Song +6 more
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Application of different types of CRISPR/Cas-based systems in bacteria
Microbial Cell Factories, 2020 As important genome editing tools, CRISPR/Cas systems, especially those based on type II Cas9 and type V Cas12a, are widely used in genetic and metabolic engineering of bacteria.
Zhenquan Liu +4 more
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