Results 251 to 260 of about 54,706 (289)

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

And… cut! - how conformational regulation of CRISPR-Cas effectors directs nuclease activity. [PDF]

Biochem J
Calvert RW, Knott GJ.
europepmc   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Artificial Intelligence-Assisted CRISPR/Cas Systems for Targeting Plant Viruses. [PDF]

Genes (Basel)
Iksat N, Madirov A, Zhanassova K, Masalimov Z.   +3 more
europepmc   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

Phage induction of Staphylococcus aureus pathogenicity islands promotes the CRISPR-Cas adaptive immune response. [PDF]

Cell Rep
Banh DV, Goldberg GW, Marraffini LA.
europepmc   +1 more source

Conformational dynamics of CRISPR-Cas type I-F-HNH inform nickase engineering in a cascade scaffold. [PDF]

Nucleic Acids Res
Fuglsang A, Rout SS, Koutna EB, Sofos N, Gallego AR, Montoya G.   +5 more
europepmc   +1 more source

Orn-mediated c-di-GMP regulates the CRISPR-Cas system to confer stress response in Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Yu W, Yuan L, Zhou W, He L, Huang X, Yu J, Deng J, Zhang T, Hu Y, Zhang Y, Chen S.   +10 more
europepmc   +1 more source

Enhanced editing of <i>Bifidobacterium lactis</i> using the endogenous Type I-G CRISPR-Cas system. [PDF]

Appl Environ Microbiol
Raftopoulou O, Malmstrom K, Pan M, Barrangou R.   +3 more
europepmc   +1 more source