Results 271 to 280 of about 207,049 (372)

Coincident Fluorescence‐Burst Analysis of Actin Cargo Molecules in Secreted Single Diffusing Extracellular Vesicles From Human Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study presents a two‐color FCCS and coincident‐burst analysis platform to quantify actin cargo in dual‐labeled EVs secreted from hiPSCs. The approach tracks secretion dynamics, confirms actin loading, and measures EV size and cargo number, offering insights into cytoskeletal disruption and neuronal differentiation relevant to neurodegenerative ...
Dang Du Nguyen, Aleksandr Barulin, Won Jong Yu, Jong‐Chan Park, Inki Kim   +4 more
wiley   +1 more source

Quorum Sensing Inhibits Type III-A CRISPR-Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus. [PDF]

Adv Sci (Weinh)
Li Y, Tang Y, Li X, Høyland-Kroghsbo NM, Ingmer H, Jiao X, Li Q.   +6 more
europepmc   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

AcrIE7 inhibits the CRISPR-Cas system by directly binding to the R-loop single-stranded DNA. [PDF]

Proc Natl Acad Sci U S A
Kim DY, Lee SY, Ha HJ, Park HH.
europepmc   +1 more source

Gene Repression in Haloarchaea Using the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas I-B System [PDF]

, 2016
Aris-Edda Stachler, Anita Marchfelder
openalex   +1 more source

Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics

Advanced Science, EarlyView.
Integrated computational‐biological programming enables secure in vivo data storage by generating code tables from either genomes or gene regulatory networks, expanding the encryption key space by over 100 orders of magnitude. Storing code tables within synthetic genes, genomes, or gene regulatory networks adds an additional layer of security by ...
Jiaxin Xu, Yu Wang, Haibo Zhou, Mingen Li, Yang Wang, Lingwei Wang, Hui Mei, Junbiao Dai, Shanze Chen, Xiaoluo Huang   +9 more
wiley   +1 more source

Efficient genome editing in dicot plants using calreticulin promoter-driven CRISPR/Cas system. [PDF]

Mol Hortic
Li B, Shang Y, Wang L, Lv J, Wu Q, Wang F, Chao J, Mao J, Ding A, Wu X, Xue K, Chen C, Cui M, Sun Y, Zhang H, Dai C.   +15 more
europepmc   +1 more source

Functional Characterization of CRISPR-Cas System in the Ethanologenic Bacterium <i>Zymomonas mobilis</i> ZM4

, 2016
Ge Dong, Mingxiong He, Hong Feng
openalex   +2 more sources

A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time

Advanced Science, EarlyView.
This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li, Qiang Ning, Zhen Li, Qian Zhang, Peilu Zhu, Jimin Zhan, Yunfu Li, Zhen Li, Liang Dong, Qing Xiong, Jiahao Liao, Jie Liu, David Jackson, Munenori Kitagawa, Zuxin Zhang, Lei Liu   +15 more
wiley   +1 more source

Cas3 of type I-Fa CRISPR-Cas system upregulates bacterial biofilm formation and virulence in Acinetobacter baumannii. [PDF]

Commun Biol
Guo T, Yang J, Zhou N, Sun X, Huan C, Lin T, Bao G, Hu J, Li G.   +8 more
europepmc   +1 more source