Results 241 to 250 of about 58,663 (324)

Engineered Cas12j‐8 is a Versatile Platform for Multiplexed Genome Modulation in Mammalian Cells

Advanced Science, EarlyView.
Engineered through structure‐guided protein engineering, enCas12j‐8 significantly enhances the editing efficiency of compact Cas12j‐8 while maintaining high specificity. It enables efficient multiplexed genome editing and base editing using a single crRNA array, demonstrating broad applicability and therapeutic potential in genome engineering ...
Ru Meng, Jiayao Li, Wuke Wang, Dong Liang, Zhanwei Li, Cong Mao, Qingyang Li, Yu Zhang, Hao Chen, Jin Tang, Ping Hu, Qi Niu, Xingxu Huang, Bin Shen, Jun Zhang   +14 more
wiley   +1 more source

Phage Genetic Engineering Using CRISPR–Cas Systems [PDF]

, 2018
Asma Hatoum-Aslan
openalex   +1 more source

HIV infection detection using CRISPR/Cas systems: Present and future prospects. [PDF]

Comput Struct Biotechnol J, 2023
Deng B, Xue J.
europepmc   +1 more source

A Smart Single‐Loop‐Mediated Isothermal Amplification Facilitates Flexible SNP Probe Design for On‐Site Rapid Differentiation of SARS‐CoV‐2 Omicron Variants

Advanced Science, Volume 12, Issue 26, July 10, 2025.
The ssLAMP method amplifies the nucleic acid of pathogen and identifies SNP mutations. By combining the portable detection device with smartphone‐based analysis software, enables rapid, on‐site SNP detection and genotyping of SARS‐Cov‐2 Omicron variants, providing a cost‐effective and field‐deployable solution for precise pathogen identification in ...
Qijie Lin, Hongchao Gou, Xiaoyun Qu, Kaiyuan Jia, Yuhui Deng, Dan Li, Qianyi Cai, Yucen Liang, Xiaozhen Xu, Yanbin Li, Jianhan Lin, Letian Li, Yuhang Jiang, Shouwen Du, Lingcong Deng, Bailing Yan, Ruidong Liu, Chang Li, Jianmin Zhang, Ming Liao   +19 more
wiley   +1 more source

Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system

, 2016
Nina Molin Høyland‐Kroghsbo, Jon E. Paczkowski, Sampriti Mukherjee, Jenny M. Broniewski, Edze R. Westra, Joseph Bondy‐Denomy, Bonnie L. Bassler   +6 more
openalex   +1 more source

Characterization of CRISPR‐Cas systems in the Ralstonia solanacearum species complex [PDF]

, 2018
André da Silva Xavier, Juliana Cristina Fraleon de Almeida, Alessandra Gonçalves de Melo, Geneviève M. Rousseau, Denise M. Tremblay, Rafael Reis de Rezende, Sylvain Moineau, Poliane Alfenas‐Zerbini   +7 more
openalex   +1 more source

Relationship Between CRISPR-Cas Systems and Acquisition of Tetracycline Resistance in Non-Clinical Enterococcus Populations in Bulgaria. [PDF]

Antibiotics (Basel)
Pandova M, Kizheva Y, Hristova P.
europepmc   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Applications of the CRISPR/Cas system beyond gene editing [PDF]

, 2018
Tobias Anton, Elisabeth Karg, Sebastian Bultmann   +2 more
openalex   +1 more source

Comparative Analysis of Spacer Targets in CRISPR-Cas Systems of Starter Cultures. [PDF]

Acta Naturae
Fatkulin AA, Chuksina TA, Sorokina NP, Smykov IT, Kuraeva EV, Masezhnaya ES, Smagina KA, Shkurnikov MY.   +7 more
europepmc   +1 more source