Results 101 to 110 of about 10,210,911 (299)

Ranking Universities: Criteria and Consequences [PDF]

open access: yes, 2007
This Supplement to 'Higher Education Digest' Number 59 brings together a number of items addressing the issue of university rankings. The first piece explores some of the background to the debate: the impact of rankings, the main criticisms and broader ...
Locke, William
core  

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Semantic Criteria of Correct Formalization [PDF]

open access: yes, 2010
This paper compares several models of formalization. It articulates criteria of correct formalization and identifies their problems. All of the discussed criteria are so called “semantic” criteria, which refer to the interpretation of logical formulas ...
Lampert, Timm
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Machine Learning Models for Predicting Bioavailability of Traditional and Emerging Aromatic Contaminants in Plant Roots

open access: yesToxics
To predict the behavior of aromatic contaminants (ACs) in complex soil–plant systems, this study developed machine learning (ML) models to estimate the root concentration factor (RCF) of both traditional (e.g., polycyclic aromatic hydrocarbons ...
Siyuan Li   +8 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Research on rural domestic sewage discharge, influencing factors and pollution loads in the Yangtze river basin

open access: yesScientific Reports
In this study, the characteristics of rural domestic wastewater discharge in the Yangtze River Basin, China, are analysed via geographic information visualization, pollutant load assessment, and correlation analysis.
Junchao Li   +6 more
doaj   +1 more source

On independent permutation separability criteria

open access: yes, 2005
Recently P. Wocjan and M. Horodecki [quant-ph/0503129] gave a characterization of combinatorially independent permutation separability criteria. Combinatorial independence is a necessary condition for permutations to yield truly independent criteria ...
Clarisse, Lieven, Wocjan, Pawel
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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