Results 81 to 90 of about 6,215,927 (308)

Spatiotemporal Patterns and Driving Factors of Forest Vegetation Carbon Storage in Jiangxi Province, China (1990–2024): A Geographically Weighted Regression Approach

open access: yesRemote Sensing
Forests, as the largest terrestrial carbon sink, play a critical role in mitigating climate change. Accurately estimating forest vegetation carbon storage and identifying its drivers are essential for evaluating regional carbon sink functions and ...
Yue Gong   +6 more
doaj   +1 more source

Criteria of Validity

open access: yesThe Modern Law Review
This article revisits the debate between inclusive and exclusive legal positivism, arguing that the question around which it is founded – about whether morality can function as a condition of legal validity – obscures a more basic and fundamental truth about the nature of law: that the norms composing a legal system's criteria of validity have a formal
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Comparison of Population-Weighted Exposure Estimates of Air Pollutants Based on Multiple Geostatistical Models in Beijing, China

open access: yesToxics
Various geostatistical models have been used in epidemiological research to evaluate ambient air pollutant exposures at a fine spatial scale. Few studies have investigated the performance of different exposure models on population-weighted exposure ...
Yinghan Wu   +5 more
doaj   +1 more source

bkc-group/metaheuristic-proof-of-criteria: metaheuristic-proof-of-criteria

open access: yes, 2020
A novel consensus model called Meta-heuristic Proof of Criteria ...
tuyen97
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Towards Sustainable Utilization: A Review on Red Mud-Based Cementitious Systems from the “Earth’s Macro-Cycle” Perspective

open access: yesSustainable Chemistry
Driven by the urgent need for large-scale disposal and resource valorization of bauxite residue (red mud), this review adopts a narrative review perspective, grounded in the Earth’s Macro-Cycle concept, and employs a structured yet non-systematic ...
Junkai Chong   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Impact of COVID-19 Lockdown on Inhaled Toxic Elements in PM2.5 in Beijing: Composition Characterization and Source-Specific Health Risks Assessment

open access: yesAtmosphere
In early 2020, China experienced a mass outbreak of a novel coronavirus disease (COVID-19). With an aim to evaluate the impact of emission variations on toxic element species in PM2.5 and the health risks associated with inhalation exposure during COVID ...
Mingsheng Zhao   +5 more
doaj   +1 more source

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