Results 61 to 70 of about 2,262,136 (302)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

On the energy efficiency-spectral efficiency trade-off over the MIMO rayleigh fading channel [PDF]

open access: yes, 2012
Along with spectral efficiency (SE), energy efficiency (EE) is becoming one of the key performance evaluation criteria for communication system. These two criteria, which are conflicting, can be linked through their trade-off. The EE-SE trade-off for the
Héliot, Fabien   +2 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Simple Market Protocols for Efficient Risk Sharing [PDF]

open access: yes
This paper studies the performance of four market protocols with egard to allocative efficiency and other performance criteria such as volume or volatility.
Marco LiCalzi, Paolo Pellizzari
core   +3 more sources

Methodology and criteria for assessing the financial efficiency of agricultural clusters [PDF]

open access: yesE3S Web of Conferences
This article undertakes a thorough analysis of the methodology and criteria employed in assessing the financial efficiency of agricultural clusters.
Ilhom Ochilov
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

ASSESSING EFFICIENCY OF NATIONAL BORROWINGS ON HOME AND FOREIGN MARKETS OF SECURITIES

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2017
National debt managing is a complicated system task of top-priority, which becomes upmost important in conditions of crisis facing Russian economy today.
Viktor V. Pankov
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

On the efficiency at maximum cooling power

open access: yes, 2013
The efficiency at maximum power (EMP) of heat engines operating as generators is one corner stone of finite-time thermodynamics, the Curzon-Ahlborn efficiency $\eta_{\rm CA}$ being considered as a universal upper bound.
Apertet, Yann   +4 more
core   +1 more source

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