Results 61 to 70 of about 5,186 (164)

Domestic dogs carriers of Leishmania infantum, Leishmania tropica and Crithidia fasciculata as potential reservoirs for human visceral leishmaniasis in northeastern Iran

open access: yesVeterinary Medicine and Science, 2022
Background In recent years, cases of human visceral leishmaniasis (HVL) have been reported in some districts of Golestan Province, northeastern Iran, particularly in rural areas.
Mahdi Fakhar   +7 more
doaj   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone   +15 more
wiley   +1 more source

Development of a TaqMan qPCR assay for trypanosomatid multi-species detection and quantification in insects

open access: yesParasites & Vectors, 2023
Background Trypanosomatid parasites are widely distributed in nature and can have a monoxenous or dixenous life-cycle. These parasites thrive in a wide number of insect orders, some of which have an important economic and environmental value, such as ...
Olga Barranco-Gómez   +8 more
doaj   +1 more source

Microbial Pressure and Social Immunity: Bumble Bees Increase Brood Hygiene After Exposure to a Bacillus thuringiensis‐Based Biopesticide

open access: yesEcology and Evolution, Volume 16, Issue 6, June 2026.
In social insect colonies, diseased or dead brood is identified and removed by workers to prevent the infection of the whole colony. Here, bumble bee larvae exposed to a bacterium (Bacillus thuringiensis ssp. aizawai (strain: ABTS‐1857)) based biopesticide were removed more frequently than wounded or untreated control larvae. This shows that bumble bee
Michelle Scheffler   +4 more
wiley   +1 more source

Stunning Intricacies of RNA Editing Complexes RECC, RESC, and REH2C: Functional Organization, Developmental Regulation, and Evolutionary History in Kinetoplastid Protists

open access: yesWIREs RNA, Volume 17, Issue 2, March/April 2026.
U‐indel RNA editing targets mRNA:gRNA duplexes through three key complexes that collectively govern assembly, specificity, catalysis, and developmental regulation. Modern tools, including artificial intelligence, analyze the organization, dynamics, and evolution of the remarkable holo‐editosome, opening new avenues in RNA biology and therapy.
Suzanne M. McDermott   +18 more
wiley   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

open access: yesThe FEBS Journal, Volume 293, Issue 6, Page 1681-1707, March 2026.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk   +8 more
wiley   +1 more source

Agricultural intensification shapes community composition and parasite prevalence of native but not introduced bumble bees

open access: yesBasic and Applied Ecology
Bumble bees are important pollinators of crops and native plants, yet face widespread declines linked to agricultural intensification and parasite pressure.
Jenna B. Melanson   +4 more
doaj   +1 more source

Integrating the Microbiome Into Infection Ecology and Evolution in Wild Animals

open access: yesMolecular Ecology, Volume 35, Issue 5, March 2026.
ABSTRACT Parasites are a ubiquitous force in nature threatening wildlife populations and ecosystems. Interactions between hosts and their parasites are impacted by host‐associated microbiomes, which are essential for host development, physiology and immunity.
Jingdi Li   +5 more
wiley   +1 more source

Multiple Key Hosts and Network Structure Shape Viral Prevalence Across Multispecies Communities of Bees

open access: yesEcology Letters, Volume 29, Issue 2, February 2026.
This study develops a quantitative framework that integrates field data, epidemiological models, simulations, and Bayesian inference to identify key viral hosts in multispecies bee communities. By estimating species‐specific R0 values from flower‐visitor networks and viral screening, we show that honeybees, as well as other wild bees, can drive the ...
Patrycja Pluta   +4 more
wiley   +1 more source

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