Results 101 to 110 of about 1,997,752 (267)

Effects of Esketamine Versus Remifentanil on Hemodynamics and Prognosis in Patients with Septic Shock Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial

Drug Design, Development and Therapy
Yuting Li, Hongxiang Li, Feng Zhang, Yumeng Chen, Dong Zhang Department of Critical Care Medicine, The First Hospital of Jilin University, Changchun, Jilin, People’s Republic of ChinaCorrespondence: Dong Zhang, Email zhangdong@jlu.edu.cnBackground ...
Li Y, Li H, Zhang F, Chen Y, Zhang D
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Equity of Access to Critical Care Among Elderly Patients in Scotland

, 2015
Annemarie B Docherty, Niall Anderson, Timothy Walsh, Nazir Lone   +3 more
openalex   +2 more sources

Promoting interprofessional collaboration in a critical care unit in Singapore: nursing perspectives [PDF]

, 2016
Yanika Kowitlawakul, Janet Mei-Peng Lam, Chew Lai Sum, Chun Mei Lim, Zauyah bte Sanif   +4 more
openalex   +1 more source

Retracted: Clinical Brain Death with False Positive Radionuclide Cerebral Perfusion Scans

Case Reports in Critical Care, 2016
Case Reports in Critical Care
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Implication of heart rate variability in critical care medicine

, 2005
Bonpei Takase
openalex   +2 more sources

The effects of interactive E-learning on delirium recognition ability and delirium-related strain of care among critical care nurses [PDF]

, 2020
Tahereh Najafi Ghezeljeh, Fatemeh Rahnamaei, Soghra Omrani, Shima Haghani   +3 more
openalex   +1 more source

A case of hemodiafiltration dialysis preventing progression of acute kidney injury in a patient with hypermyoglobinemia in one kidney: a case report

Journal of Medical Case Reports
Background Rhabdomyolysis is a clinical syndrome resulting from skeletal muscle damage and the release of its breakdown products into the bloodstream. It can range from asymptomatic cases to severe conditions such as acute kidney injury.
Toru Minamiyama, Shozo Yoshida, Yosuke Mizuno, Hiroki Kitagaki, Kaori Kimura, Yoshihito Naito, Akihiro Uchida, Ayumi Kuroda, Yuki Kawasaki, Ayane Nishio, Hirotsugu Fukuda, Genki Yoshimura, Ryo Kamidani, Takahito Miyake, Norihide Kanda, Hideshi Okada   +15 more
doaj   +1 more source