Results 121 to 130 of about 5,260,453 (314)

Metabolomic Profiling by UPLC-QTOF/MS Reveals Potential Biomarkers and Metabolic Alterations in Pediatric Septic Shock

Journal of Inflammation Research
Changxue Xiao,* Chenhao Wang,* Sa Wang, Feng Xu, Yingfu Chen Department of Critical Care Medicine, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of ...
Xiao C, Wang C, Wang S, Xu F, Chen Y
doaj  

Home care workers: keeping Granite Staters in their homes as they age [PDF]

, 2009
Using data from the New Hampshire Direct Care Workforce Survey, this brief shows that New Hampshire\u27s demand for home-based care workers outpaces supply because its population is aging at a faster rate than the average.
Smith, Kristin
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Retracted: Clinical Brain Death with False Positive Radionuclide Cerebral Perfusion Scans

Case Reports in Critical Care, 2016
Case Reports in Critical Care
doaj   +1 more source

Endotracheal Oxygen Insufflation Associated with Life-Threatening Barotrauma during Apnea Testing

Case Reports in Neurological Medicine
Apnea testing is a standard method when diagnosing brain or more specifically brainstem death; however, it is imperative to acknowledge the potential for lung injury during this procedure and follow clinical practice guideline recommendations that may ...
Saud Ali Aljasir, Fahad Abdullah Alshammari, Jehan Abdullah Abdul-aziz Fatani, Abdalrhman Al Saadon, Abdulaziz H. Alzeer   +4 more
doaj   +1 more source

Public Health Law: A Renaissance [PDF]

, 2002
Public health seeks to assure the conditions for people to be healthy. Public health can be distinguished from health care in several critical respects.
Gostin, Lawrence O.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Adolescent Health Services: Missing Opportunities [PDF]

, 2008
Examines the status of adolescents' health and health services, including critical needs, promising models, and components for improving disease prevention and health promotion.
Jennifer Appleton Gootman, Leslie J. Sim, Robert S. Lawrence   +2 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source