Results 131 to 140 of about 10,286,525 (296)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

From FEV1 to Small Airways: A Methodological Review of Lung Function Assessment in Biologic-Treated Asthma

Journal of Asthma and Allergy
Hai-Ling Yang, Ya-Jia Chen, Xue-Qiong Mai, Xiao-Ling Zou, Wenwen Ding, Shao-Zhu WuDepartment of Pulmonary and Critical Care Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Institute of Respiratory Diseases of Sun Yat-sen University ...
Yang HL, Chen YJ, Mai XQ, Zou XL, Ding W, Wu SZ   +5 more
doaj  

Critical Care Nurses' Motivation Toward Their Work: Psychometric Evaluation of the Critical Care Nursing Motivation Scale. [PDF]

Nurs Crit Care
Lawz HA, Türkoğlu N, Dumit N, Ikkawi A, Deek H.   +4 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

The Effect of Donor Packed Cell Volume and Storage Characteristics on Transfusion Efficacy in Cats

Veterinary Medicine: Research and Reports
Brynna Lee, Kelly Chambers, Rebecca Wendth, Jennifer Prittie, Alicia Mastrocco, Joel G WeltmanEmergency and Critical Care Department, Schwarzman Animal Medical Center, New York, NY, USACorrespondence: Brynna Lee, Emergency and Critical Care Department ...
Lee B, Chambers K, Wendth R, Prittie J, Mastrocco A, Weltman JG   +5 more
doaj  

INTENSIVE CRITICAL CARE

Lung India, 2022
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

National adult critical care capacity and activity census 2017

, 2018
The annual national adult Critical Care Bed Capacity Census measures capacity as at 30th September 2017. The Census reports a capacity of 240 adult critical care (Level3 ICU and Level2 HDU) beds.
HSE Acute Hospitals Division, Critical Care Programme   +1 more
core  

Neonatal Critical Care Nursing. [PDF]

Nurs Crit Care
McCarter DL, Gallagher K.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source