Results 151 to 160 of about 12,324,592 (318)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Critical care transfers [PDF]

Anaesthesia, 2011
A, Inglis, A, Cadamy, R, Price, G, Rutherford   +3 more
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Prognostic Value of SIRI in Sepsis: A Retrospective Study and Machine Learning-Based Model Development

Journal of Inflammation Research
Yilin Zhu,1,* Zhiyang Wang,2,* Shifeng Li,3,* Xin Xiao,3 Yujie Liu,3 Jiachen He,3 Fang Huang,3 Jun Wang3 1Department of Critical Care Medicine, Zhangjiagang Hospital Affiliated to Soochow University/The First People’s Hospital of ...
Zhu Y, Wang Z, Li S, Xiao X, Liu Y, He J, Huang F, Wang J   +7 more
doaj  

Artificial intelligence in emergency medicine critical care. [PDF]

Clin Exp Emerg Med
Heslin SM, Nocito R, Weingart SD.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

How to perform fluid de-escalation in critical care. [PDF]

Ann Intensive Care
Bircher RE, Ostini A, Pfortmueller CA, Messmer AS.   +3 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Antifreeze Poisoning Complicated by Severe Metabolic Acidosis, Toxic Encephalopathy, and Multiple Organ Dysfunction Syndrome: A Case Report

Open Access Emergency Medicine
Min Liu,1– 3 Yayuan Tan,1– 3 Yinchun Xie,1,4 Jinglan Liu,1– 3 Haishuang Mei,1– 3 Dan Jin,1– 3 Zhaohui Zhang1– 3 1Department of Intensive Medicine, The First College of Clinical Medical Science, China Three Gorges University, Yichang, Hubei, People’s ...
Liu M, Tan Y, Xie Y, Liu J, Mei H, Jin D, Zhang Z   +6 more
doaj  

Airway management strategies in critical care. [PDF]

Am J Respir Crit Care Med
Coursen JC, Enoh SE, Miller HL, Montemayor K.   +3 more
europepmc   +1 more source