Results 81 to 90 of about 10,286,525 (296)

Critical care nurses' assessment of patients' anxiety: Reliance on physiological and behavioral parameters

, 2020
BACKGROUND Anxiety activates the sympathetic nervous system and hypothalamic-pituitary-adrenal axis and may increase morbidity and mortality in vulnerable critical care patients. Despite the adverse effects of anxiety, little is known about critical care
안경애
core   +1 more source

Risk Factors and Predictive Value of Sepsis in Patients with Liver Abscess

Infection and Drug Resistance
Xiaoyan Ma,1,2 Yanni Chen,3 Xing An,3 Jie Zhang,3 Xigang Ma41Department of Critical Care Medicine, Yinchuan First People’s Hospital, Yinchuan, Ningxia, 750001, People’s Republic of China; 2The Second Clinical Medical College, Ningxia Medical University ...
Ma X, Chen Y, An X, Zhang J, Ma X
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nurses' perceived barriers and educational needs for early mobilisation of critical ill patients

, 2019
BACKGROUND: Early mobilisation (EM) of critically ill patients is an evidence-based intervention designed to improve treatment outcomes and enhance the quality of life after intensive care.
최모나, 김상희
core   +1 more source

To Die or Not to Die: How Sublethal Damage Rewires Cell Fate and Implications for Sepsis

Journal of Inflammation Research
Zihan Hu, Xing Zhou, Qin Sun, Lianlian Jiang, Mengfan Wu, Jianfeng Xie, Yi Yang, Fei PengJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University ...
Hu Z, Zhou X, Sun Q, Jiang L, Wu M, Xie J, Yang Y, Peng F   +7 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Deciphering Cuproptosis in Sepsis: Mechanisms, Consequences, and Therapeutic Opportunities

Journal of Inflammation Research
Ruimin Tan,1,2 Kexin Wen,1,2 Tianyu Zhao,2,3 He Guo,2,4 Xumin Han,2,4 Jiakai Wang,2,4 Chen Ge,2 Quansheng Du2 1School of Clinical Medical, North China University of Science and Technology, Tangshan, Hebei, People’s Republic of China; 2Critical Care ...
Tan R, Wen K, Zhao T, Guo H, Han X, Wang J, Ge C, Du Q   +7 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

ORAL CARE INTERVENTIONS and OROPHARYNGEAL COLONIZATION in CHILDREN RECEIVING MECHANICAL VENTILATION

, 2009
Background Recent progress in identification of oral microorganisms has shown that the oropharynx can be a site of origin for dissemination of pathogenic organisms to distant body sites, such as the lungs.Objective To compare the oropharyngeal ...
Carvalho, Werther Brunow de [UNIFESP], Nunez, Silvia Cristina, Kusahara, Denise M. [UNIFESP], Pedreira, Mavilde L. G. [UNIFESP], Peterlini, Maria Angelica S. [UNIFESP]   +4 more
core   +1 more source

Critical Care Guidance for Tracheostomy Care During the COVID-19 Pandemic: A Global, Multidisciplinary Approach

, 2020
Purpose Critical care nurses caring for patients with a tracheostomy are at high risk because of the predilection of SARS-CoV-2 for respiratory and mucosal surfaces.
Okusanya, Kafilat Ajoke, Walsh, Brian, Morris, LL, Walsh, B, Okusanya, KA, Brodsky, Martin B., Brodsky, MB, McGrath, BA, Rushton, Cynda, Sole, ML, Lambe, Leah, Paredes Garza, Francisco, Zavalis, Andrea, Brenner, Michael J., Lynch, J, Lambe, L, DeRose, Troy, Palmieri, PA, Pandian, Vinciya, Lami, L, Pandian, V, Maiani, Simona, McGrath, Brendan A.; id_orcid, Davidson, Patricia, DeRose, T, Maiani, S, Palmieri, Patrick A., Rahman, A, Morris, Linda L., Phillips, Jane, Zavalis, A, Pelosi, P, Pelosi, Paolo, Lynch, James, Rushton, C, Lami, Lionel, Davidson, P, Phillips, J, Garza, FP, Wu, Sarah Pui Man, Sole, Mary Lou, Man Wu, SP, Rahman, Alphonsa, Brenner, MJ   +43 more
core   +1 more source