Results 131 to 140 of about 14,005,591 (363)

33 * INTERVENTIONS TO PREVENT NON-CRITICAL CARE HOSPITAL ACQUIRED PNEUMONIA-A SYSTEMATIC REVIEW [PDF]

open access: bronze, 2015
S. M. McAuley   +5 more
openalex   +1 more source

Technology adoption in health care: International barriers and opportunities to telemedicine [PDF]

open access: yes, 2014
Although telemedicine and telehealth are seen as discrete entities by some authors, both The Cochrane Library (2010) and the WHO (2009) acknowledge that definitions overlap.
Carter, Bernie
core   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

An Analysis of Major Issues for Culturally-Minded Professionals in Women\u27s Health Care [PDF]

open access: yes, 2019
Women\u27s health care professionals, such as general physicians, obstetricians and gynecologists, midwives, nurses, and doulas, in the US need to be aware of cultural issues and disparities.
Clark, Victoria
core   +1 more source

Monro-Kellie 2.0: The dynamic vascular and venous pathophysiological components of intracranial pressure [PDF]

open access: yes, 2016
For 200 years, the ‘closed box’ analogy of intracranial pressure (ICP) has underpinned neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine stating that a change in blood, brain or CSF volume resulted in reciprocal ...
Wilson, MH
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

A Simplified Immune-Dysregulation Index (IL-6/LY) as a Robust Predictor of 28-Day In-Hospital Mortality and MODS in Patients with Sepsis

open access: yesJournal of Inflammation Research
Meili Liu,1,2,* Tao You,3,* Shifeng Li,1,* Yan Hao,1,* Zhiyang Wang,1 Fang Huang,1 Jun Wang1 1Department of Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China ...
Liu M   +6 more
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Deciphering Cuproptosis in Sepsis: Mechanisms, Consequences, and Therapeutic Opportunities

open access: yesJournal of Inflammation Research
Ruimin Tan,1,2 Kexin Wen,1,2 Tianyu Zhao,2,3 He Guo,2,4 Xumin Han,2,4 Jiakai Wang,2,4 Chen Ge,2 Quansheng Du2 1School of Clinical Medical, North China University of Science and Technology, Tangshan, Hebei, People’s Republic of China; 2Critical Care ...
Tan R   +7 more
doaj  

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