Results 151 to 160 of about 1,997,752 (267)

Pain Management in Paediatric Critical Care: A Cross-Sectional Study. [PDF]

Nurs Crit Care
Laures E, LaFond C, McCarthy AM.
europepmc   +1 more source

Ginsenoside Rg3 Mitigates LPS-Induced Injury in Human Bronchial Epithelial Cells by Restoring Autophagic Flux and Inhibiting the TLR4/NF-κB-Mediated Inflammatory Response

Journal of Inflammation Research
Xingyu Tao,1– 4,* Lingjiao Liu,1– 3,* Xiaoke Gu,5 Baohui Jia,6 Qi Yu,1– 3 Yingying Wei,1– 3 Wei Zhang,1– 3 Jing Zhou1– 3 1Department of Respiratory and Critical Care Medicine, Jiangxi Medical College, Nanchang University, The First ...
Tao X, Liu L, Gu X, Jia B, Yu Q, Wei Y, Zhang W, Zhou J   +7 more
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Encouraging direct discharges home from Critical Care. [PDF]

J Intensive Care Soc
Crossingham I.
europepmc   +1 more source

Critical care medicine: technology and patient management. Introduction [PDF]

, 1990
J H Eckfeldt
openalex   +1 more source

Identification of developing multiple organ failure in sepsis patients with low or moderate SOFA scores

Critical Care, 2018
Gunnar Elke, Frank Bloos, Darius Cameron Wilson, Patrick Meybohm, the SepNet Critical Care Trials Group   +4 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Future of critical care: a blueprint for building sustainable cardiac critical care capacity. [PDF]

Ann Transl Med
Franko L, Nikolic I, Kwo J, Bagchi A, D'Alessandro D, Sundt T, Shelton KT.   +6 more
europepmc   +1 more source

Cost Analysis Of Targeted Temperature Management In Critical Care: A United States Hospital Perspective [PDF]

, 2014
P. Delatore, Mattias Martinson, Nicole Ferko, Derek Tran   +3 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source