Results 71 to 80 of about 13,388,670 (413)

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Neutrophil-Lymphocyte Ratio in Patients with Hypertriglyceridemic Pancreatitis Predicts Persistent Organ Failure

Gastroenterology Research and Practice, 2022
Background. The neutrophil–lymphocyte ratio (NLR) has been proposed as a surrogate marker of inflammation with prognostic value in various diseases. Our objective was to investigate the predictive value of the NLR as an indicator of persistent organ ...
Zhihua Lu, Xiangping Chen, Huiqing Ge, Man Li, Binbin Feng, Donghai Wang, Feng Guo   +6 more
doaj   +1 more source

Classic Papers in Critical Care: A Bibliometric Analysis [PDF]

, 2019
Purpose- This study aimed to identify and analyze the bibliometric characteristics of the classic papers in the field of critical care. Design/methodology/approach- In this bibliometric overview, Google Scholar, Scopus and Web of Science were used for ...
Esmaeilzadeh, Maryam, Mahdiyoun, Seyed Ali, Mokhtari, Heidar   +2 more
core   +1 more source

The health and social consequences of an alcohol related admission to critical care: a qualitative study [PDF]

, 2016
Objective: To examine the impact of critical care on future alcohol-related behaviour. Further, it aimed to explore patterns of recovery for patients with and without alcohol use disorders beyond the hospital environment.
Forrest, Ewan, Kinsella, John, McPeake, Joanne, O'Neill, Anna, Quasim, Tara   +4 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Critical Psychiatry [PDF]

, 2007
Critical psychiatry appraises and comments upon psychiatric services as they are usually provided. This article, prompted by the publication of a recent book, considers the place of critical psychiatry historically and in the context of contemporary ...
Middleton, Hugh
core   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Days spent on non-invasive ventilation support: can it determine when to initiate VV- ECMO? Observational study in a cohort of Covid-19 patients

BMC Pulmonary Medicine, 2023
Background The study evaluates the impact of the time between commencing non-invasive ventilation (NIV) support and initiation of venovenous extracorporeal membrane oxygenation (VV-ECMO) in a cohort of critically ill patients with coronavirus disease ...
María P. Fuset-Cabanes, LLuisa Hernández-Platero, Joan Sabater-Riera, Miguel Gordillo-Benitez, Fabio Di Paolo, Paola Cárdenas-Campos, Krystel Maisterra-Santos, María Pons-Serra, Paola Sastre-Pérez, Alejandro García-Zaloña, Javiera Puentes-Yañez, Xosé Pérez-Fernández   +11 more
doaj   +1 more source

Risk Adjustment In Neurocritical care (RAIN)--prospective validation of risk prediction models for adult patients with acute traumatic brain injury to use to evaluate the optimum location and comparative costs of neurocritical care: a cohort study. [PDF]

, 2013
OBJECTIVES: To validate risk prediction models for acute traumatic brain injury (TBI) and to use the best model to evaluate the optimum location and comparative costs of neurocritical care in the NHS. DESIGN: Cohort study.
Gomes, M, Grieve, R, Griggs, KA, Harrison, DA, Harvey, SE, Hutchinson, PJA, Lecky, FE, Menon, DK, Prabhu, G, Rowan, KM, Sadique, MZ, Smith, M, Walmsley, E, Yeoman, P   +13 more
core   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source