Results 91 to 100 of about 3,413,512 (272)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
InspiringTeaching scientific writing has been compulsory in many Indonesian universities. It is usually the main indicator for completing an undergraduate program.
Siti Hadianti
doaj +1 more source
Critical Points in Distance Learning System
Social Technologies, 2013 Purpose – This article presents the results of distance learning system analysis, i.e. the critical elements of the distance learning system. The critical points of distance learning are a part of distance education online environment interactivity/community process model.
openaire +3 more sources
, 2019 Context. The precise determination of the present-day expansion rate of the Universe, expressed through the Hubble constant $H_0$, is one of the most pressing challenges in modern cosmology.
Birrer, S. +9 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Critical scaling of the quantum Wasserstein distance
Physical Review ResearchDistinguishing quantum states with minimal sampling overhead is of fundamental importance to teach quantum data to an algorithm. Recently, the quantum Wasserstein distance emerged from the theory of quantum optimal transport as a promising tool in this ...
Gonzalo Camacho, Benedikt Fauseweh
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Intercriticism and the Myth of Critical Distance
Critical Stages, 2011 The term inter-criticism is quite clearly one that has been made up for this particular colloquium. I wasn’t sure what it meant going into this paper and, having now completed my paper, I am still not sure what it means.
Don Rubin
doaj