Results 51 to 60 of about 31,308 (311)

Existence and nonexistence of solutions for an approximation of the Paneitz problem on spheres

open access: yesBoundary Value Problems, 2023
This paper is devoted to studying the nonlinear problem with slightly subcritical and supercritical exponents ( S ± ε ) : Δ 2 u − c n Δ u + d n u = K u n + 4 n − 4 ± ε $(S_{\pm \varepsilon}): \Delta ^{2}u-c_{n}\Delta u+d_{n}u = Ku^{ \frac{n+4}{n-4}\pm ...
Kamal Ould Bouh
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Critical Exponent is Computable for Automatic Sequences

open access: yesElectronic Proceedings in Theoretical Computer Science, 2011
The critical exponent of an infinite word is defined to be the supremum of the exponent of each of its factors. For k-automatic sequences, we show that this critical exponent is always either a rational number or infinite, and its value is computable ...
Jeffrey Shallit
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On a p-Laplacian system with critical Hardy–Sobolev exponents and critical Sobolev exponents [PDF]

open access: yesUkrainian Mathematical Journal, 2012
In this paper, the existence results of positive solutions for the semiliner elliptic system \[ \begin{cases} -\text{div} (|\nabla u_i|^{p-2} \nabla u_i) - \mu \frac{|u_i|^{p-2}u_i}{|x|^p} \\ = \frac{1}{p^*} F_{u_i}(u_1,\ldots,u_k) + \frac{|u_i|^{p^*(t)-2}u_i}{|x|^t} + \lambda \frac{|u_i|^{p-2}u_i}{|x|^s}, \quad x \in \Omega, \\ u_i=0 \quad \text{on} \;
openaire   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Schrodinger-Poisson systems with singular potential and critical exponent

open access: yesElectronic Journal of Differential Equations, 2020
In this article we study the Schrodinger-Poisson system $$\displaylines{ -\Delta u +V(|x|)u+\lambda\phi u = f(u), \quad x\in\mathbb{R}^3, \cr -\Delta \phi =u^2, \quad x\in\mathbb{R}^3, }$$ where V is a singular potential with the parameter $\alpha ...
Senli Liu, Haibo Chen, Zhaosheng Feng
doaj  

Critical exponent of binary words with few distinct palindromes [PDF]

open access: green, 2023
Ľubomíra Dvořáková   +2 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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