Results 91 to 100 of about 4,116,169 (343)

Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota

Nature Communications, 2020
Bioorthogonal non-canonical amino acid tagging (BONCAT) coupled with flow cytometry (FACS) has been utilized to profile active microbiome of environmental samples.
Talia D. Valentini, Sarah K. Lucas, Kelsey A. Binder, Lydia C. Cameron, Jason A. Motl, Jordan M. Dunitz, Ryan C. Hunter   +6 more
doaj   +1 more source

Near-critical free-surface flows: real fluid flow analysis [PDF]

Environmental Fluid Mechanics, 2010
An open channel flow with a flow depth close to the critical depth is characterised by a curvilinear streamline flow field that results in steady free surface undulations. Near critical flows of practical relevance encompass the undular hydraulic jump when the flow changes from supercritical (F > 1) to subcritical (F < 1), and the undular weir flow ...
Castro-Orguaz, Oscar, Chanson, Hubert
openaire   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Landau critical velocity in weakly interacting Bose gases

, 2012
The flow of a uniform Bose gas at speeds greater than the Landau critical velocity, v_c, does not necessarily destroy superfluidity, but rather need only lead to a decrease of the superfluid mass density, {\rho}_s. Analyzing a weakly interacting Bose gas
C. J. Pethick, Gordon Baym, L. D. Landau, L. P. Pitaevskii, L. P. Pitaevskii   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Flow-critical graphs

Lovász et al. proved that every $6$-edge-connected graph has a nowhere-zero $3$-flow. In fact, they proved a more technical statement which says that there exists a nowhere zero $3$-flow that extends the flow prescribed on the incident edges of a single vertex $z$ with bounded degree. We extend this theorem of Lovász et al.
Árnadóttir, Arnbjörg Soffía, Dvořák, Zdeněk, Lidický, Bernard, Moore, Benjamin, Smith-Roberge, Evelyne, Šámal, Robert   +5 more
openaire   +2 more sources

Entry effects of droplet in a micro confinement: implications for deformation-based CTC microfiltration

, 2015
Deformation based circulating tumor cell (CTC) microchips are a representative diagnostic device for early cancer detection. This type of device usually involves a process of CTC trapping in a confined microgeometry. Further understanding of the CTC flow
Chen, Xiaolin, Xu, Jie, Zhang, Zhifeng
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The Critical Conditions of Filtration Flow Blocking in a Porous Channel with Phase Transitions [PDF]

Journal of Heat and Mass Transfer Research
The paper studies the occurrence of kinetic phase transitions in porous media with thermodynamic phase transitions, which affect filtration flow through permeability or viscosity: in the simplest case, permeability is a step function of local temperature.
Igor Donskoy
doaj   +1 more source