Results 131 to 140 of about 6,342,270 (352)

The Perception of Critical Success Factors for PPP Projects in Different Stakeholder Groups

open access: yesEntrepreneurial Business and Economics Review, 2016
Objective:  The main goal of the research is to enhance understanding which factors are perceived as critical for the success of public-private partnerships (PPPs) by different stakeholder groups on different stages of the project life cycle.
Joanna Węgrzyn
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Oxygen Functional Groups on MWCNT Surface as Critical Factor Boosting T2 Relaxation Rate of Water Protons: Towards Improved CNT-Based Contrast Agents

open access: yesInternational Journal of Nanomedicine, 2020
Mateusz Michał Tomczyk,1 Sławomir Boncel,1 Artur Herman,2 Tomasz Krawczyk,1 Agata Jakóbik-Kolon,1 Mirosława Pawlyta,3 Maciej Krzywiecki,4 Artur Chrobak,5 Masafumi Minoshima,6 Fuminori Sugihara,7 Kazuya Kikuchi,6 Nikodem Kuźnik1 1Faculty of ...
Tomczyk MM   +11 more
doaj  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Multiple solutions to asymmetric semilinear elliptic problems via Morse theory

open access: yesElectronic Journal of Differential Equations, 2014
In this article we study the existence of solutions to the problem $$\displylines{ -\Delta u = g(x,u) \quad \text{in } \Omega; \cr u = 0 \quad\text{on } \partial\Omega, }$$ where $\Omega$ is a smooth bounded domain in $\mathbb{R}^N$ $(N\geq 2)$
Leandro L. Recova, Adolfo J. Rumbos
doaj  

Harmonic Morphisms of Arithmetical Structures on Graphs [PDF]

open access: yesarXiv
Let $\phi \colon \Gamma_2 \rightarrow \Gamma_1$ be a harmonic morphism of connected graphs. We show that an arithmetical structure on $\Gamma_1$ can be pulled back via $\phi$ to an arithmetical structure on $\Gamma_2$. We then show that some results of Baker and Norine on the critical groups for the usual Laplacian extend to arithmetical critical ...
arxiv  

Cyclic Critical Groups of Graphs

open access: yes, 2015
In this note, we describe a construction that leads to families of graphs whose critical groups are cyclic. For some of these families we are able to give a formula for the number of spanning trees of the graph, which then determines the group exactly. We also pose several open questions related to this work.
Becker, Ryan, Glass, Darren
openaire   +2 more sources

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

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