We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Generalized chip firing and critical groups of arithmetical structures on trees [PDF]
Kassie Archer +3 more
openalex +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
An elliptic equation involving the square root of the Laplacian without asymptotic limits
Yutong Chen +3 more
doaj
'Aint We Women?' A Narrative Review of Intensive and Acute Care Experiences of Black Women Through an Intersectional Lens. [PDF]
Kusi-Appiah E +4 more
europepmc +1 more source
Critical Sobolev, Gagliardo-Nirenberg, Trudinger and Brezis-Gallouet-Wainger inequalities, best constants, and ground states on graded groups [PDF]
Michael Ruzhansky +1 more
openalex
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Consolidation-to-ground-glass opacity ratio on chest CT as a prognostic marker for critical outcomes in COVID-19: a retrospective cohort study. [PDF]
Tanaka H +33 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Multiple solutions for semilinear Robin problems with superlinear reaction and no symmetries
Nikolaos S. Papageorgiou +2 more
doaj

