The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression. [PDF]
, 2016 Basal-like breast cancers (BLBCs) are aggressive breast cancers associated with poor survival. Defining the key drivers of BLBC growth will allow identification of molecules for targeted therapy.
Brown, Powel H +6 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Singularly Perturbed Fractional Schrödinger Equations with Critical Growth
Advanced Nonlinear Studies, 2018 We are concerned with the following singularly perturbed fractional Schrödinger equation:
He Yi
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The efficiency of individual optimization in the conditions of competitive growth
, 2009 The paper aims to discuss statistical properties of the multi-agent based model of competitive growth. Each of the agents is described by growth (or decay) rule of its virtual "mass" with the rate affected by the interaction with other agents.
Aoyama +35 more
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Electronic Journal of Differential Equations, 2013 In this work, we study the existence and multiplicity of solutions for a class of problems involving the $\phi$-Laplacian operator in a bounded domain, where the nonlinearity has a critical growth.
Jefferson A. Santos
doaj
Nonequilibrium behaviors of 3D Heisenberg model in the Swendsen-Wang algorithm
, 2015 Recently Y. N. showed that the nonequilibrium critical relaxation of the 2D Ising model from the perfectly-ordered state in the Wolff algorithm is described by the stretched-exponential decay, and found a universal scaling scheme to connect ...
Nonomura, Yoshihiko, Tomita, Yusuke
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Critical Limits for Soybean and Black Bean Root Growth, Based on Macroporosity and Penetrability, for Soils with Distinct Texture and Management Systems [PDF]
, 2022 Luis Eduardo Akiyoshi Sanches Suzuki +3 more
openalex +1 more source