Results 131 to 140 of about 11,751,266 (377)

Expected number of critical points of random holomorphic sections over complex projective space [PDF]

open access: yesarXiv, 2017
We study the high dimensional asymptotics of the expected number of critical points of a given Morse index of Gaussian random holomorphic sections over complex projective space. We explicitly compute the exponential growth rate of the expected number of critical points of the largest index and of diverging indices at various rates as well as the ...
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Multiple solutions of an elliptic Hardy-Sobolev equation with critical exponents on compact Riemannian manifolds [PDF]

open access: yesarXiv, 2019
On a compact Riemannian manifold, we prove the existence of multiple solutions for an elliptic equation with critical Sobolev growth and critical Hardy potential.
arxiv  

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

On some multiple solutions for a $p(x)$-Laplace equation with supercritical growth [PDF]

open access: yesarXiv
We consider the multiplicity of solutions for the $p(x)$-Laplacian problems involving the supercritical Sobolev growth via Ricceri's principle. By means of the truncation combining with De Giorgi iteration, we can extend the result about subcritical and critical growth to the supercritical growth and obtain at least three solutions for the $p(x ...
arxiv  

On the constrained growth of complex critical systems [PDF]

open access: yesarXiv, 2012
Critical, or scale independent, systems are so ubiquitous, that gaining theoretical insights on their nature and properties has many direct repercussions in social and natural sciences. In this report, we start from the simplest possible growth model for critical systems and deduce constraints in their growth : the well-known preferential attachment ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Multiplicity of solutions for quasilinear equations involving critical Orlicz-Sobolev nonlinear terms

open access: yesElectronic Journal of Differential Equations, 2013
In this work, we study the existence and multiplicity of solutions for a class of problems involving the $\phi$-Laplacian operator in a bounded domain, where the nonlinearity has a critical growth.
Jefferson A. Santos
doaj  

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