Results 51 to 60 of about 11,751,266 (377)
Fractional elliptic problems with critical growth in the whole of $\R^n$ [PDF]
We study the following nonlinear and nonlocal elliptic equation in~$\R^n$ $$ (-\Delta)^s u = \epsilon\,h\,u^q + u^p \ {\mbox{ in }}\R^n, $$ where~$s\in(0,1)$, $n>2s$, $\epsilon>0$ is a small parameter, $p=\frac{n+2s}{n-2s}$, $q\in(0,1)$, and~$h\in L^1(\R^
S. Dipierro, María Medina, E. Valdinoci
semanticscholar +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
New multiple positive solutions for elliptic equations with singularity and critical growth
In this note, the existence of multiple positive solutions is established for a semilinear elliptic equation $ -\Delta u=\frac{\lambda}{u^\gamma}+u^{2^*-1},~x\in\Omega,~u=0, x\in\partial\Omega$, where $\Omega$ is a smooth bounded domain in $\mathbb{R}^N$
Hongmin Suo, Chunyu Lei, Jia-Feng Liao
doaj +1 more source
We study the asymptotic profile, as ℏ→0{\hbar\rightarrow 0}, of positive solutions ...
Cassani Daniele, Wang Youjun
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
In this paper, we study the multiplicity and concentration of solutions for the following critical fractional Schrodinger–Poisson system: \begin{eqnarray*} \left\{ \begin{array}{ll} \epsilon^{2s}(-\triangle)^{s} {u}+ V(x)u+\phi u =f(u)+|u|^{2^*_{s}-2}u &\
Zhisu Liu, Jianjun Zhang
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Nucleation and growth by diffusion under Ostwald-Freundlich boundary condition [PDF]
The critical radius of a nucleus grown by diffusion in a solution is studied thermodynamically as well as kinetically. The thermodynamic growth equation called Zeldovich equation of classical nucleation theory (CNT) and the kinetic diffusional growth equation combined with the Ostwald-Freundlich boundary condition lead to the same critical radius ...
arxiv +1 more source