Results 101 to 110 of about 6,679,818 (388)

Leukocyte telomere length in paediatric critical illness [PDF]

, 2018
__Background:__ Children who have suffered from critical illnesses that required treatment in a paediatric intensive care unit (PICU) have long-term physical and neurodevelopmental impairments. The mechanisms underlying this legacy remain largely unknown.
C. Ingels (Catherine), Derese, I. (Inge), Guerra, G.G. (Gonzalo Garcia), Hanot, J. (Jan), J. Lin (Jue), Joosten, K.F.M. (Koen), Puffelen, E. (Esther) van, Van den Berghe, G. (Greet), Vanhorebeek, I. (Ilse), Verbruggen, S.C.A.T. (Sascha), Verstraete, S. (Sören), Vlasselaers, D. (Dirk), Wouters, P.J. (Pieter)   +12 more
core   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Impact of Stress‐Induced Hyperglycemia on In‐Hospital Medical Complications in Patients With Acute Stroke: From a Large‐Scale Nationwide Longitudinal Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song, Yi Ju, Hongqiu Gu, Zhikai Zhu, Zixiao Li, Qian Zhang, Xingquan Zhao   +6 more
wiley   +1 more source

The hypothalamic-pituitary-adrenal axis in critical illness [PDF]

, 1993
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Allolio, B., Reincke, Martin, Winkelmann, W., Würth, G.   +3 more
core  

Statin therapy in critical illness : an international survey of intensive care physicians' opinions, attitudes and practice [PDF]

, 2012
Background Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure.
Di Gangi, Stefania, Kruger, Peter S., McAuley, Danny F., Perkins, Gavin D., Scales, Damon C., Shankar-Hari, Manu, Terblanche, Marius   +6 more
core   +1 more source

Prevalence and Course of Frailty in Survivors of Critical Illness*

Critical Care Medicine, 2020
Supplemental Digital Content is available in the text. Objectives: Little is known about frailty that develops following critical illness. We sought to describe the prevalence of newly acquired frailty, its clinical course, and the co-occurrence of ...
N. Brummel, T. Girard, P. Pandharipande, Jennifer L. Thompson, Ryan T. Jarrett, R. Raman, C. Hughes, Mayur B. Patel, A. Morandi, T. Gill, E. W. Ely   +10 more
semanticscholar   +1 more source

Where, how, and how much? A multicenter cohort study of the relationship between lupus decision aid modality, place of administration, interruption and viewing completeness and patient‐reported outcomes

Arthritis Care &Research, Accepted Article.
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh, Mark Beasley, Larry R. Hearld, for the Implementing DEcision‐Aid for Lupus in clinics (IDEAL) Consortium   +3 more
wiley   +1 more source

The Economic Burden of Rheumatoid Arthritis in Low‐ and Middle‐Income Countries: Systematic Review and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Objective The aim of this systematic review was to synthesise the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye, Chidozie E.Mbada, Clara T.Fatoye, Faatihah Niyi‐Odumosu, Ushotanefe Useh, Zalmai Hakimi, Francis Fatoye   +6 more
wiley   +1 more source

Rehabilitation after critical illness: could a ward-based generic rehabilitation assistant promote recovery? [PDF]

, 2010
Lisa Salisbury - ORCID: 0000-0002-1400-3224 https://orcid.org/0000-0002-1400-3224Item is not available in this repository.Aim: The aim of this paper is to explore issues surrounding the implementation of a generic rehabilitation assistant (GRA) to ...
Bailey, Bernhardt, Collen, Combes, Crichton, Cuthbertson, Cuthbertson, Cuthbertson, Department of Health, Elliott, Felder-Alford, Griffiths, Herridge, Jones, Jones, Kalra, Klidjian, Mahoney, Moran, Morris, Nava, Nelson, Pettila, Podsiadlo, Priestley, Pullenayegum, Stanmore, Steffen, Stiller, Stroke Unit Trialists' Collaboration, Stucki, van der Schaff, Wade, Ware, Ware, Ware   +35 more
core   +1 more source

Nutrition therapy and critical illness: practical guidance for the ICU, post-ICU, and long-term convalescence phases

Critical Care, 2019
BackgroundAlthough mortality due to critical illness has fallen over decades, the number of patients with long-term functional disabilities has increased, leading to impaired quality of life and significant healthcare costs.
A. V. van Zanten, E. de Waele, P. Wischmeyer   +2 more
semanticscholar   +1 more source