Results 161 to 170 of about 510,057 (296)

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

Advanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling, Chongxin Wu, Mengxuan Gui, Kaiyun Chen, Yanbo Yang, Jiwei Xing, Fengxian Du, Wei Liao, Luyao Yang, Zhaokui Jin, Ningshao Xia, Guosong Wang, Yixin Chen, Qingliang Zhao   +13 more
wiley   +1 more source

Comment on the CIBCD model for chronic critical illness. [PDF]

Crit Care
Likhvantsev VV, Yadgarov MY, Yakovlev AA, Berikashvili LB.   +3 more
europepmc   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

Moving from Critical Illness Syndromes toward Biologic Molecular Endotypes: Making Progress. [PDF]

Am J Respir Crit Care Med
Laffey JG, Giamarellos-Bourboulis EJ.
europepmc   +1 more source

Complex dynamics of skin sympathetic nerve activities provides mechanistic insights into critical-illness and are prognostic predictors

, 2020
Jien‐Jiun Chen, Chen Lin, Men-Tzung Lo, Lian‐Yu Lin   +3 more
openalex   +1 more source

Posttraumatic Stress Disorder Symptom Clusters in Surrogate Decision Makers of Patients Experiencing Chronic Critical Illness

, 2022
Blair Wendlandt, Agathe Ceppe, Bradley N. Gaynes, Christopher E. Cox, Laura C. Hanson, Judith E. Nelson, Shannon S. Carson   +6 more
openalex   +1 more source

Robust Physics‐Informed Neural Network Approach for Estimating Heterogeneous Elastic Properties from Noisy Displacement Data

Advanced Science, EarlyView.
Heterogeneous distributions of elasticity parameters are learned from noisy displacement data using the Inverse Elasticity Physics‐Informed Neural Network (IE‐PINN). This approach integrates both data‐driven and physics‐driven methods to address the significant limitations faced by existing techniques.
Tatthapong Srikitrungruang, Sina Aghaee Dabaghan Fard, Matthew Lemon, Jaesung Lee, Yuxiao Zhou   +4 more
wiley   +1 more source

Proposing a novel ABCDEF framework for managing critical illness in geriatrics: challenges and perspectives. [PDF]

Ann Med
Shen J, Yan J, Xie J, Li L.
europepmc   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Family Experiences of Financial Hardship after Critical Illness. [PDF]

Ann Am Thorac Soc
Ashana DC.
europepmc   +1 more source