Results 181 to 190 of about 5,699,579 (389)

Structural Diversity of Mitochondria in the Neuromuscular System across Development Revealed by 3D Electron Microscopy

open access: yesAdvanced Science, EarlyView.
Mitochondria across the entire neuromuscular system have been comprehensively reconstructed at different developmental stages using 3D electron microscopy. Fundamental structural principles related to synaptic function are preserved across development, and these morphologies are adapted to ensure effective neural circuit function.
J. Alexander Bae   +9 more
wiley   +1 more source

Patterns of community violence exposure among urban adolescents and their associations with adjustment

open access: yesAmerican Journal of Community Psychology, Volume 70, Issue 3-4, Page 265-277, December 2022., 2022
Abstract Community violence exposure is prevalent among urban and marginalized adolescents. Although there is strong evidence that community violence exposure is associated with negative consequences, prior studies and theories suggest that these associations may differ as a function of specific characteristics of exposure.
Sarah K. Pittman, Albert D. Farrell
wiley   +1 more source

Interleukin-2 Initiates Metabolic Responses Associated with Critical Illness in Humans

open access: green, 1988
H. R. Michie   +5 more
openalex   +2 more sources

Large‐Area Conductor‐Loaded PDMS Flexible Composites for Wireless and Chipless Electromagnetic Multiplexed Temperature Sensors

open access: yesAdvanced Science, EarlyView.
This work demonstrates the first chipless temperature sensing array based on conductor‐loaded composites. They allow multiple items to be simultaneously identified and monitored through multiplexed electromagnetic reflections. The work studies the influence of conductive fillers on the frequency‐domain properties of PDMS, for the first time.
Benjamin King   +2 more
wiley   +1 more source

The Achieved Capabilities Questionnaire for Community Mental Health (ACQ‐CMH): A consumer‐based measure for the evaluation of community mental health interventions

open access: yesAmerican Journal of Community Psychology, Volume 70, Issue 3-4, Page 327-339, December 2022., 2022
Abstract The capabilities approach offers a multidimensional, ecological, and agent‐centered framework that may inspire models of intervention and evaluation. A growing number of measures grounded on the capabilities approach for outcome measurement are appearing.
Beatrice Sacchetto   +2 more
wiley   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

open access: yesAdvanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong   +20 more
wiley   +1 more source

CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length

open access: yesAdvanced Science, EarlyView.
This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo   +5 more
wiley   +1 more source

An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR‐Addicted Lung Tumorigenesis

open access: yesAdvanced Science, EarlyView.
The study identifies agrin‐EGFR mechanotransduction as a critical driver of lung adenocarcinoma which enhances EGFR signaling through an integrin‐FAK‐actomyosin dependent positive feedback on YAP/TAZ ‐TEAD in response to matrix stiffness. Targeting this oncogenic loop through combinatorial treatments inhibits lung cancer due to agrin impairment.
Reza Bayat Mokhtari   +20 more
wiley   +1 more source

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