Results 211 to 220 of about 510,057 (296)

Inappropriate Empirical Antibiotic Therapy and Mortality in Critical Illness: A Retrospective Cohort Study with Propensity Score Analysis in an Indonesian ICU

Riska Yulinta Viandini, Wiwi Jaya, Arie Zainul Fatoni   +2 more
openalex   +2 more sources

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

Advanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye, Xiaoli Zhang, Lingfeng Qiu, Jia Ji, Jueqing Gu, Hongyu Jia, Yingfeng Lu, Jiyang Chen, Zelu Meng, Jiangshan Lian, Hangping Yao, Xun Zeng, Yida Yang   +12 more
wiley   +1 more source

Sarcopenia and frailty in critical illness. [PDF]

Curr Opin Clin Nutr Metab Care
van der Steen-Dieperink MJMM, Koekkoek WAC, Kouw IWK.   +2 more
europepmc   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

Advanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu, Leyi Wang, Tao Lv, Chen Jin, Qiong Wu, Yongjie Zhou, Gang Xu, Zhenyu Duan, Kui Luo, Jiayin Yang   +9 more
wiley   +1 more source

Gas as medicine: the case for hydrogen gas as a therapeutic agent for critical illness. [PDF]

Intensive Care Med Exp
Chawla LS.
europepmc   +1 more source

Understanding Disseminated Intravascular Coagulation and Hepatobiliary Dysfunction Multiple Organ Failure in Hyperferritinemic Critical Illness*

, 2018
Joseph A. Carcillo, Bita Shakoory, Dennis Simon, Kate F. Kernan   +3 more
openalex   +2 more sources

A Clarification on Quantum‐Metric‐Induced Nonlinear Transport

Advanced Science, EarlyView.
How does the quantum metric truly govern the nonlinear transport? The longstanding theoretical discrepancies are resolved in quantum‐metric‐induced nonlinear transport and the correct intrinsic nonlinear conductivity is identified. Furthermore, a toy model is engineered to suppress the competing effects, uniquely highlighting the role of quantum metric
Xiao‐Bin Qiang, Tianyu Liu, Zi‐Xuan Gao, Hai‐Zhou Lu, X. C. Xie   +4 more
wiley   +1 more source

Post-resuscitation Critical Illness Dysphagia: A Case Report. [PDF]

Cureus
Hassan AMM, Shah S, Bustamante N, Solano J.   +3 more
europepmc   +1 more source

Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex

Advanced Science, EarlyView.
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano, Yulia Dembitskaya, Ivo Calaresu, Somen Nandi, Quentin Gresil, Evelyne Doudnikoff, Thierry Leste‐Lasserre, Thierry Amédée, Laurent Cognet, Laurent Groc, Urs Valentin Nägerl, Erwan Bezard   +11 more
wiley   +1 more source

Targeting the Dynamics Between TAMs and CAR‐T Cells in Solid Tumor Therapies

Advanced Science, EarlyView.
This review highlights the critical role of tumor‐associated macrophages (TAMs) in affecting CAR‐T cell therapy effectiveness in solid tumors. TAMs contribute to immune suppression through cytokine secretion, immune checkpoint activation, and metabolic reprogramming, leading to CAR‐T cell exhaustion and reduced efficacy. The article explores strategies
Xiang Zhang, Hao Zheng, Zi‐Chang Liu, Ling‐Jie Luo, Xiao Dong, Xin‐Gang Cui, Yan‐Wei Wu, Liang Chen   +7 more
wiley   +1 more source