Results 241 to 250 of about 6,679,818 (388)

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

open access: yesAdvanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu   +18 more
wiley   +1 more source

Cerebrospinal Fluid in Critical Illness

open access: hybrid, 2000
Balasubramanian Venkatesh   +2 more
openalex   +1 more source

Critical illness-implications of non-thyroidal illness syndrome and thyroxine therapy. [PDF]

open access: yesWorld J Crit Care Med
Savvidis C   +7 more
europepmc   +1 more source

Intrinsic Photo‐Crosslinkable Semiconductive Small‐Molecule Crystals (i‐PSSCs) for Patterning Electronic Devices

open access: yesAdvanced Science, EarlyView.
A novel intrinsic photo‐crosslinkable semiconductive small molecule is designed and synthesized. The solution‐processed crystalline film can be patterned by in situ photopolymerization under UV light irradiation without external crosslinking agents, and the crystalline order and charge transport properties are preserved, demonstrating potential for ...
Huaqing Li   +7 more
wiley   +1 more source

Spatiotemporal Characterization of the Functional MRI Latency Structure with Respect to Neural Signaling and Brain Hierarchy

open access: yesAdvanced Science, EarlyView.
Resting‐state fMRI captures intrinsic brain activity, yet the physical significance of latency structures remains unclear. In this study, the spatiotemporal properties of fMRI‐derived latency structures are examined by linking them to biophysical model‐based neural functions, intrinsic neural timescales, and functional gradients.
Hyoungshin Choi   +5 more
wiley   +1 more source

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

open access: yesAdvanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin   +7 more
wiley   +1 more source

SYMPATHOINHIBITION IN CRITICAL ILLNESS DURING MECHANICAL CIRCULATORY SUPPORT

open access: bronze, 2000
Tatsuo Tsutsui   +7 more
openalex   +1 more source

A Novel in Vivo Rabbit Model of Hypercatabolic Critical Illness Reveals a Biphasic Neuroendocrine Stress Response [PDF]

open access: bronze, 2002
Frank Weekers   +6 more
openalex   +1 more source

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