Results 261 to 270 of about 6,560,806 (389)

Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles

open access: yesAdvanced Science, EarlyView.
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu   +13 more
wiley   +1 more source

Metabolic, Endocrine, and Immune Effects of Stress Hyperglycemia in a Rabbit Model of Prolonged Critical Illness [PDF]

open access: bronze, 2003
Frank Weekers   +6 more
openalex   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

open access: yesAdvanced Science, EarlyView.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda   +12 more
wiley   +1 more source

Synthesis of Diaryl‐ and Dialkynylphosphinates From Ubiquitous PV Sources via a Redox‐Neutral Approach

open access: yesAdvanced Science, EarlyView.
Classical strategies for P─C bond formation rely on precursors (e.g., PH3, H2PO2, PCl3) obtained from P4, which is produced via the energy‐intensive thermal process. Here, an alternative, redox‐neutral approach is explored. Primary phosphate sources are activated with triflic anhydride (Tf2O) and 4‐dimethylaminopyridine (DMAP) to a versatile PV ...
Tobias Schneider   +5 more
wiley   +1 more source

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