Highly Penetrant Genetic Disorders: An Atlas for Critical Illness Insurance [PDF]
Angus S. Macdonald, Shuyu Yang
openalex +1 more source
Novel Swelling‐Lytic Cell Death Triggered by Cargo‐Free Ionizable Lipid Nanoparticles
A cargo‐free ionizable lipid nanoparticles (ipLNP) is found to induce broad swelling‐lytic cell death across multiple cell types. Cell death may be associated with lysosome membrane destabilization, involving ROS increase, lipid peroxidation, and GSDME cleavage.
Junjun Wu+13 more
wiley +1 more source
Metabolic, Endocrine, and Immune Effects of Stress Hyperglycemia in a Rabbit Model of Prolonged Critical Illness [PDF]
Frank Weekers+6 more
openalex +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda+12 more
wiley +1 more source
Circulating Secretory Phospholipase A2 in Critical Illness - The Importance of the Intestine
Charlie Corke+2 more
openalex +1 more source
Endocrine and Metabolic Effects of Growth Hormone (GH) Compared with GH-Releasing Peptide, Thyrotropin-Releasing Hormone, and Insulin Infusion in a Rabbit Model of Prolonged Critical Illness [PDF]
Frank Weekers+6 more
openalex +1 more source
Classical strategies for P─C bond formation rely on precursors (e.g., PH3, H2PO2, PCl3) obtained from P4, which is produced via the energy‐intensive thermal process. Here, an alternative, redox‐neutral approach is explored. Primary phosphate sources are activated with triflic anhydride (Tf2O) and 4‐dimethylaminopyridine (DMAP) to a versatile PV ...
Tobias Schneider+5 more
wiley +1 more source
Effect of an Educational Intervention on Nurses' Knowledge Regarding Use of Modified Early Warning Score in Recognition of Critical Illness. [PDF]
Olowo S, Luwaga R, Niyonzima V.
europepmc +1 more source