Results 81 to 90 of about 6,957,076 (388)

Factors associated with missed assessments in a 2-year longitudinal study of acute respiratory distress syndrome survivors

BMC Medical Research Methodology, 2018
Background To evaluate participant-related variables associated with missing assessment(s) at follow-up visits during a longitudinal research study. Methods This is a prospective, longitudinal, multi-site study of 196 acute respiratory distress syndrome (
Sara E. Heins, Amy W. Wozniak, Elizabeth Colantuoni, Kristin A. Sepulveda, Pedro A. Mendez-Tellez, Cheryl Dennison-Himmelfarb, Dale M. Needham, Victor D. Dinglas   +7 more
doaj   +1 more source

Natural Product Alantolactone Targeting AKR1C1 Suppresses Cell Proliferation and Metastasis in Non-Small-Cell Lung Cancer

Frontiers in Pharmacology, 2022
Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, characterized by high invasion and metastasis. Aldo-keto reductase family 1 member C1 (AKR1C1) plays an important role in cancer cell proliferation and metastasis ...
Zhiwen Fu, Zhiwen Fu, Shijun Li, Shijun Li, Jinmei Liu, Jinmei Liu, Cong Zhang, Cong Zhang, Chen Jian, Chen Jian, Lulu Wang, Lulu Wang, Yu Zhang, Yu Zhang, Chen Shi, Chen Shi   +15 more
doaj   +1 more source

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Psychopolitics: Peter Sedgwick’s legacy for mental health movements [PDF]

, 2009
This paper re-considers the relevance of Peter Sedgwick's Psychopolitics (1982) for a politics of mental health. Psychopolitics offered an indictment of ‘anti-psychiatry’ the failure of which, Sedgwick argued, lay in its deconstruction of the category of
A Bell, A Gamble, A Harrison, A James, A Plumb, B Skeggs, C Leys, C Offe, D Coates, D Lecourt, D Pilgrim, D Pilgrim, DB Double, E Goffman, E Laclau, E Laclau, E Laclau, F Furedi, G Agamben, G Bachelard, G Burchell, G Szmukler, H Spandler, H Spandler, H Spandler, H Wainwright, H Wainwright, Helen Spandler, I Parker, J Freeman, J Habermas, J Habermas, J Read, JL Herman, K Marx, K Marx, KWM Fulford, L Blackman, L Johnstone, L Pembroke, M Castells, M Cresswell, M Cresswell, M Cresswell, M Cresswell, M Foucault, M Fuster, M Romme, Mark Cresswell, N Crossley, N Crossley, N Crossley, N Crossley, P Bracken, P Breggin, P Campbell, P Campbell, P Du Gay, P Kropotkin, P Sedgwick, P Sedgwick, P Sedgwick, P Sedgwick, R Castel, R Coleman, RD Laing, S Hall, S Rowbotham, T Curtis, T Szasz, T Szasz, T Wilton, V Serge, W Brown, Z Papacharissi   +74 more
core   +1 more source

Innate immune training in the neonatal response to sepsis

Molecular Medicine
Neonates, especially those born prematurely, are highly vulnerable to infection-induced mortality. Numerous observational and immunological studies in newborns have shown that live attenuated vaccines have beneficial, non-specific effects (NSEs) against ...
Jaimar C. Rincon, Dayuan Wang, Valerie E. Polcz, Evan L. Barrios, Marvin L. Dirain, Ricardo F. Ungaro, Dina C. Nacionales, Leilani Zeumer-Spataro, Feifei Xiao, Philip A. Efron, Lyle L. Moldawer, Guoshuai Cai, Shawn D. Larson   +12 more
doaj   +1 more source

Assessment of Sarcopenia in the Intensive Care Unit and 1-Year Mortality in Survivors of Critical Illness [PDF]

, 2021
Naoya Yanagi, Tomotaka Koike, Kentaro Kamiya, Nobuaki Hamazaki, Kohei Nozaki, Takafumi Ichikawa, Atsuhiko Matsunaga, Masayuki Kuroiwa, Masayasu Arai   +8 more
openalex   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Risk factors for bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation: a systematic review and meta-analysis

BMC Pulmonary Medicine
Background Bronchiolitis obliterans syndrome (BOS) after hematopoietic stem cell transplantation (HSCT) is a late-onset complication that significantly impairs patients’ quality of life and is associated with a high mortality rate.
Guangchen Pu, Guangmin Nong, Qing Wei, Yunyan He, Wenguang Jia, Zhenhao Lu, Guosheng Qiu, Jun Xie, Xun Chen   +8 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Implementing nudges to promote utilization of low tidal volume ventilation (INPUT): a stepped-wedge, hybrid type III trial of strategies to improve evidence-based mechanical ventilation management

Implementation Science, 2021
Background Behavioral economic insights have yielded strategies to overcome implementation barriers. For example, default strategies and accountable justification strategies have improved adherence to best practices in clinical settings.
Meeta Prasad Kerlin, Dylan Small, Barry D. Fuchs, Mark E. Mikkelsen, Wei Wang, Teresa Tran, Stefania Scott, Aerielle Belk, Jasmine A. Silvestri, Tamar Klaiman, Scott D. Halpern, Rinad S. Beidas   +11 more
doaj   +1 more source