Results 81 to 90 of about 6,679,818 (388)

Psychopolitics: Peter Sedgwick’s legacy for mental health movements [PDF]

open access: yes, 2009
This paper re-considers the relevance of Peter Sedgwick's Psychopolitics (1982) for a politics of mental health. Psychopolitics offered an indictment of ‘anti-psychiatry’ the failure of which, Sedgwick argued, lay in its deconstruction of the category of
A Bell   +74 more
core   +1 more source

Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

open access: yesCritical Care, 2020
Background COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host response to this virus.
J. Bermejo-Martín   +65 more
semanticscholar   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

2010 Annual Evidence Update on Critical Illness Rehabilitation [PDF]

open access: yes, 2010
For this annual evidence update a detailed literature review was undertaken to retrieve any evidence published subsequent to the literature search which formed the basis for the NICE guideline.
Gibson, Vanessa   +5 more
core  

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto   +5 more
wiley   +1 more source

Implementing nudges to promote utilization of low tidal volume ventilation (INPUT): a stepped-wedge, hybrid type III trial of strategies to improve evidence-based mechanical ventilation management

open access: yesImplementation Science, 2021
Background Behavioral economic insights have yielded strategies to overcome implementation barriers. For example, default strategies and accountable justification strategies have improved adherence to best practices in clinical settings.
Meeta Prasad Kerlin   +11 more
doaj   +1 more source

Prevalence of and Recovery From Anemia Following Hospitalization for Critical Illness Among Adults

open access: yesJAMA Network Open, 2020
Key Points Question Is anemia in patients with critical illness associated with persistent anemia following discharge? Findings In this cohort study of 6901 adults hospitalized for critical illness, 41% had prevalent anemia preceding hospitalization and ...
M. Warner   +6 more
semanticscholar   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

Innate immune training in the neonatal response to sepsis

open access: yesMolecular Medicine
Neonates, especially those born prematurely, are highly vulnerable to infection-induced mortality. Numerous observational and immunological studies in newborns have shown that live attenuated vaccines have beneficial, non-specific effects (NSEs) against ...
Jaimar C. Rincon   +12 more
doaj   +1 more source

Safety monitoring in inactivated COVID-19 vaccines by clinical pharmacists from a single center in China

open access: yesFrontiers in Immunology, 2022
Given that vaccine-induced adverse effects were mostly based on previous laboratory research and clinical trials, real-world data on the safety of coronavirus disease 2019 (COVID-19) vaccination were lacking.
Min Hu   +15 more
doaj   +1 more source

Home - About - Disclaimer - Privacy