Results 91 to 100 of about 10,947,423 (301)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Description of critical state for sands considering particle crushing
Yantu gongcheng xuebao, 2017 In recent years, granular soil is widely used in more and more earth-rockfill dams and high-filled projects being built. However, particle crushing of granular soil can not be ignored as the particle crushing of granular soil under high stress is very ...
LUO Ting , LIU Lin , YAO Yang-ping
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Influence of particle crushing on the critical state line of rockfill materials [PDF]
E3S Web of ConferencesThe mechanical behaviour of rockfill materials is strongly affected by particle breakage, which causes a continuous variation of the grain size distribution (GSD) until a stationary condition.
Ventini Roberta +3 more
doaj +1 more source
, 2007 Cost reduction, time to market, product quality improvement, and the support of technological evolution are all critical issues that software companies must face to be competitive in today's market.
Mannion, Mike; id_orcid +6 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Riemann Zeta Function Near the Critical Line
, 2011 See the values of the Riemann zeta function near the critical line in the complex plane. The height of the surface gives the absolute value; the color gives the phaseComponente Curricular::Educação Superior::Ciências Exatas e da Terra ...
Wolfram, Stephen, Trott, Michael
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Italian Journal of MedicineCentral line-associated bloodstream infections (CLABSIs) are severe bloodstream infections caused by catheter use and are often associated with a longer hospital stay, increased healthcare costs, and a higher mortality rate.
Ohoud Alhumaidan +7 more
doaj +1 more source
Critical Learning in the on-line classroom
Proceedings of the International Conference on Networked Learning, 2018 Teaching in an online classroom is often new to university teachers which highlights the importance of training and development for faculty in on-line instruction in order to realise the promise of this burgeoning form of delivery. However, current research that examines formal training initiatives offered by universities tends to promote an ...
Rasha Goumaa, Amanda Hay
openaire +1 more source
Lost and Finding: Experiences of Newly Graduated Critical Social Workers [PDF]
, 2019 The first year of social work practice can be very stressful for new practitioners. Practice develops in response to the meaning we place on what we do and on our professional goals.
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