Results 61 to 70 of about 424,711 (307)

Vulnerability of water resource management to climate change: Application to a Pyrenean valley

Journal of Hydrology: Regional Studies, 2022
Study region:: The Aure Valley in the French Pyrenees. Study focus:: This study applies a bottom-up framework for assessing water management vulnerability in terms of hydropower production, environmental regulations, and reservoir storage management by ...
Peng Huang, Eric Sauquet, Jean-Philippe Vidal, Natacha Da Riba   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

New Approaches in Dynamic Metrics for Lighting Control Systems: A Critical Review

Applied Sciences
The growing number of daylighting metrics—often overlapping in scope or terminology—combined with the need for prior familiarization to interpret and apply them effectively, has created a barrier to their adoption beyond academic settings.
Guillermo García-Martín, Miguel Ángel Campano, Ignacio Acosta, Pedro Bustamante   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Indoor Positioning Systems as Critical Infrastructure: An Assessment for Enhanced Location-Based Services

Sensors
As the demand for context-aware services in smart environments continues to rise, Indoor Positioning Systems (IPSs) have evolved from auxiliary technologies into indispensable components of mission-critical infrastructure.
Tesfay Gidey Hailu, Xiansheng Guo, Haonan Si   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Critical Infrastructure Protection: Metrics and Tools [PDF]

, 2008
Program for Critical Infrastructure Protection Workshop: Metrics and Tools; 5-7 June 2008Workshop organized by the Naval Postgraduate School Center for Homeland Defense and Security. Key topics of the conference included (1) Metrics, a discussion of how

core  

Digital Traces in Context| Otherwise Engaged: Social Media from Vanity Metrics to Critical Analytics

International Journal of Communication, 2018
Vanity metrics is a term that captures the measurement and display of how well one is doing in the “success theater” of social media. The notion of vanity metrics implies a critique of metrics concerning both the object of measurement as well as their ...
Richard Rogers
doaj  

Evaluating the efficacy of HRZE-based regimens in a high-burden murine model: a back-translational assessment of rifamycins and moxifloxacin substitutions in tuberculosis treatment

Frontiers in Pharmacology
IntroductionThe standard treatment for tuberculosis is the isoniazid, rifampicin, pyrazinamide, and ethambutol (HRZE) regimen. Despite its efficacy, this regimen has limitations, including prolonged treatment duration and poor clinical outcomes in drug ...
Jason E. Cummings, Lisa K. Woolhiser, Vincent Guglielmi, Machenzie Wernsman, Ashley Romano, Samantha Pauly, Samantha Pauly, John T. Belisle, Nicholas D. Walter, Nicholas D. Walter, Nicholas D. Walter, Gregory T. Robertson, Gregory T. Robertson, Richard A. Slayden   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source