Results 71 to 80 of about 424,711 (307)

Critical Infrastructure Protection Metrics and Tools; Prioritizing Assets in Critical Infrastructure [June 5-7, 2008] [video] [PDF]

open access: yes, 2008
The article of record may be found here: http://www.hsdl.org/?view&did=704582Conference Paper presented at Critical Infrastructure Protection Workshop: Metrics and Tools; 5-7 June 2008This video is of Hilda Blanco's presentation for the Critical ...
Blanco, Hilda
core  

A Framework for successful new product development

open access: yesJournal of Industrial Engineering and Management, 2011
Purpose: The purpose of this paper is to propose a framework of critical success factors, metrics, and tools and techniques for implementing metrics for each stage of the new product development (NPD) process.Design/methodology/approach: To achieve this ...
Nadia Bhuiyan
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Reconceptualizing Reliability Indices as Metrics to Quantify Power Distribution System Resilience

open access: yesEnergies
In regions heavily affected by recurrent typhoons, the need for more resilient electricity infrastructure is pressing. This emphasizes the importance of integrating resilience assessment, including incorporating resilience metrics, into the planning ...
Gerald A. Abantao   +12 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Torsion and critical metrics on contact three-manifolds [PDF]

open access: yesKodai Mathematical Journal, 1990
Let M be a 3-dimensional compact contact manifold with contact form \(\omega\) and characteristic vector field \(X_ 0\). Let \({\mathcal M}\) denote the set of all associated metrics to \(\omega\). For any \(g\in {\mathcal M}\) let r denote the scalar curvature, S the Ricci tensor, \(\tau\) the Lie derivative of g with respect to \(x_ 0\) and \(\sigma\)
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Critical metrics of the 𝐿²-norm of the scalar curvature [PDF]

open access: yesProceedings of the American Mathematical Society, 2014
In this paper we investigate complete critical metrics of the L 2 L^{
openaire   +4 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Identifying core nodes in interaction graphs for critical component analysis in cascading failures of power grids [PDF]

open access: yesArchives of Electrical Engineering
This paper introduces a novel approach to identifying critical lines in power systems during cascading failures, addressing significant limitations in previous methodologies such as computational inefficiency and limited effectiveness.
Francisco Rivas-Dávalos   +2 more
doaj   +1 more source

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