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The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Spontaneously interacting qubits from Gauss-Bonnet
Building on previous constructions examining how a collection of small, locally interacting quantum systems might emerge via spontaneous symmetry breaking from a single-particle system of high dimension, we consider a larger family of geometric loss ...
Sean Prudhoe +2 more
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Ecologically Inspired Metrics for Rare Earth Element Critical Material Systems [PDF]
Greenhouse gas emission reduction targets have increased demand for clean energy technologies, and the growth required for these technologies has led to concern over material availability and criticality.
Hubler, Berlyn Jo
core +1 more source
Towards employing metrics in measuring the quality of software safety critical systems and managing their development [PDF]
Failures in safety critical systems have a high impact on the environment in which they are used. For that, developers usually follow specific development standards and techniques to avoid and reduce failures in such systems.
Din, Jamilah +3 more
core +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Einstein and conformally flat critical metrics of the volume functional [PDF]
Let R R be a constant. Let M γ R \mathcal {M}^R_\gamma be the space of smooth metrics g g on a given compact manifold Ω n \Omega ^
TAM, Luen-Fai +3 more
core +1 more source
Integrating diversity and agency into social-ecological resilience metrics
Resilience is an increasingly popular concept in research and practice, but quantitative resilience analyses are often disconnected from resilience theory.
Vitor Hirata Sanches +11 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A validation metrics framework for safety-critical software-intensive systems [PDF]
Validation of safety-critical software requirements is a difficult and frequently misunderstood task. It answers the question of "are we building the right product?" and is essential to Software Engineering.
Cruickshank, Kristian John.
core

