Results 91 to 100 of about 60,314 (313)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Blending induced variations in Poloxamer's/Pluronic's® gelation: Thermodynamic and rheological perspectives

JCIS Open
Amphiphilic block copolymers (ABCs) are currently significant in pharmaceutical sciences because of their specific capability to develop various structures that are highly efficient for drug delivery. Poloxamers, sometimes referred to as Pluronic's®, are
Mohammad Qutub, Amol Tatode, Tanvi Premchandani, Jayshree Taksande, Dadaso Mane, Milind Umekar   +5 more
doaj   +1 more source

Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia [PDF]

, 2012
This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH), based on Pluronic® block copolymers, by a new microfluidic approach.
Brognara, Eleonora, Capretto, Lorenzo, Carugo, Dario, Gambari, Roberto, Hill, Martyn, Lampronti, Ilaria, Mazzitelli, Stefania, Nastruzzi, Claudio, Zhang, Xunli   +8 more
core   +2 more sources

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity

Advanced Healthcare Materials, EarlyView.
A new oxaliplatin‐based Pt(IV) prodrug bearing a Mn(II) superoxide dismutase mimic is synthesized and studied, in vitro and in vivo, in the context of colorectal cancer. Encapsulation of this prodrug in an easy‐to‐implement PEGylated micelle formulation demonstrated the highest in vivo anticancer activity among all the tested conditions, supporting the
Alvaro Lopez‐Sanchez, Henri Chédotal, Ram Pravin Kumar Muthuramalingam, Marine Thomas, Jia Ning Nicolette Yau, Priya Ranjan Sahoo, Clotilde Policar, Frédéric Batteux, Kadda Medjoubi, Andrea Somogyi, Giulia Adriani, Carole Nicco, Romain Coriat, Giorgia Pastorin, Hélène C. Bertrand   +14 more
wiley   +1 more source

The method of selecting a foaming agent and its concentration in the production of non-autoclaved hard cellular concrete

MATEC Web of Conferences, 2018
The paper considers the approach to the selection of the foaming agent and its concentration in the production of non-autoclaved hard cellular concrete, consisting in measuring the basic physico-chemical properties and determining the critical ...
Gorbach Pavel, Shcherbin Sergey, Savenkov Andrei   +2 more
doaj   +1 more source

Application of rhamnolipid biosurfactant produced by Pseudomonas aeruginosa in microbial-enhanced oil recovery (MEOR)

Journal of Petroleum Exploration and Production Technology, 2019
In this study, the biosurfactant produced by Pseudomonas aeruginosa was evaluated in view of its ability to be used in Microbial-Enhanced Oil Recovery (MEOR).
J. M. D. A. Câmara, M. A. S. B. Sousa, E. L. Barros Neto, M. C. A. Oliveira   +3 more
doaj   +1 more source

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Structure-Properties Relationship of Dimeric Surfactants from Butyl Glucosides

Molecules, 2000
Carbohydrate containing dimeric surfactants were synthesized starting from Dglucose. Three different spacers were used to link the sugar moieties. The critical micelle concentration (CMC) for these new compounds was determined.
Alicia Fernández Cirelli, José Kovensky, Mariano J. L. Castro   +2 more
doaj   +1 more source