Results 91 to 100 of about 6,548,421 (205)

Difficult Peripheral Venous Access in Children: An International Survey and Critical Appraisal of Assessment Tools and Escalation Pathways

, 2019
Background: Peripheral venous cannulation is considered a routine procedure, yet 50% of first attempt insertions fail, necessitating repeat insertion attempts.
Tricia Kleidon, Schults, Jessica, Claire Rickard, Ullman, Amanda, Kleidon, Tricia, Fiona Macfarlane, Jessica Schults, Macfarlane, Fiona, Amanda Ullman, Rebecca Paterson, Rickard, Claire, Paterson, Rebecca   +11 more
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Urban pathways towards circularity in critical raw materials: Exploring the role and actions for municipalities

Cleaner and Responsible Consumption
Cities play a pivotal role in addressing the growing criticality of raw materials essential for low-carbon and digital technologies, yet the circular management of critical raw materials (CRMs) remains weakly integrated into urban circular economy ...
Mona Arnold, Henna Sundqvist, Katri Valkokari   +2 more
doaj   +1 more source

Biological Activities and Signaling Pathways of the Granulin/Epithelin precursor.

, 1999
Growth-regulated cells, such as 3T3 mouse embryo fibroblasts (MEFs), require more than one growth factor for growth, usually the insulin-like growth factor I (IGF-I) in combination with either platelet-derived growth factor or epidermal growth factor ...
G, VALENTINIS, A, ROMANO, B, ZANOCCO MARANI, Tommaso, R. BIOLOGICAL ACTIVITIES AND SIGNALING PATHWAYS OF THE GRANULINEPITHELIN PRECURSOR, T, BATEMAN, ZHI HENG, HE, AND BASERGA   +8 more
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The evolution of Chest pain pathways

, 2011
Patients presenting to the emergency department with chest pain require prompt identification and referral, as early treatment of patients with an acute coronary syndrome (ACS) is crucial to decrease morbidity and mortality (Steurer et al, Emerg Med J ...
Scott, Adam Charles, Cullen, Louise, Louise Cullen, Mangleson, Frances Iris Jean, Scott, Adam, Frances Iris Jean Mangleson, Adam Charles Scott   +6 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Implantación de un programa de tratamiento integral de la pared abdominal: hernia incisional y abdominoplastia Resultados preliminares

Revista Colombiana de Cirugía
Introducción. Las vías clínicas son planes asistenciales sistematizados para determinados procesos hospitalarios, que constituyen una herramienta que coordina a múltiples profesionales implicados en un objetivo común.
Alfredo Moreno-Egea, Víctor Soria-Aledo, Germán Morales-Cuenca   +2 more
doaj  

Sputum Exosomal microRNAs Profiling Reveals Critical Pathways Modulated By Pseudomonas aeruginosa Colonization In Bronchiectasis

International Journal of COPD, 2019
Yan Huang,1 Chun-lan Chen,1 Jing-jing Yuan,1 Hui-min Li,1 Xiao-rong Han,1 Rong-chang Chen,2 Wei-jie Guan,1 Nan-shan Zhong1 1Department of Respiratory Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory
Huang Y, Chen C, Yuan J, Li H, Han X, Chen R, Guan W, Zhong N   +7 more
doaj  

CESCA Newsletter

, 2013
On 15 March 2013, the Center for Embedded Systems for Critical Applications is organizing a public event to present its ongoing research projects.. The theme of the symposium is Embedded Security.
Virginia Tech. Center for Embedded Systems for Critical Applications
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