Results 101 to 110 of about 7,145,149 (347)
Finding critical points whose polarization is also a critical point
, 2011 We show that near any given minimizing sequence of paths for the mountain pass lemma, there exists a critical point whose polarization is also a critical point. This is motivated by the fact that if any polarization of a critical point is also a critical point and the Euler-Lagrange equation is a second-order semi-linear elliptic problem, T. Bartsch, T.
SQUASSINA, Marco, Van Schaftingen J.
openaire +4 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 1990 A simple proof of a theorem of H. Hopf [1], via Morse theory, is given.
Takis Sakkalis
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Non-Gaussian fluctuations near the QCD critical point
, 2008 We study the effect of the QCD critical point on non-Gaussian moments (cumulants) of fluctuations of experimental observables in heavy-ion collisions. We find that these moments are very sensitive to the proximity of the critical point, as measured by ...
C. Schmidt +3 more
core +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Existence of multiple breathers for discrete nonlinear Schrodinger equations
Electronic Journal of Differential Equations, 2019 In this article we study discrete nonlinear Schrodinger equations without periodicity assumptions. We show the existence of multiple solutions of the form $u_n e^{-i\omega t}$ (called breathers) by using Clark's Theorem in critical point theory.
Tao Zhou +3 more
doaj
Indications of a ferromagnetic quantum critical point in [Formula: see text]. [PDF]
Sci Rep, 2023 Holmes-Hewett WF +6 more
europepmc +1 more source
Trajectories joining critical points
Journal of Differential Equations, 1982 In this paper we shall be concerned with the existence of trajectories joining a pair of critical points, or more generally, a pair of compact invariant sets. Our framework will be abstract dynamical systems. We shall present applications and examples among both finite and infinite dimensional differential equations.
M. Slemrod, Zvi Artstein
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Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
QCD critical point: Recent developments [PDF]
EPJ Web of ConferencesRecent developments aimed at mapping QCD phase diagram and the search for the QCD critical point in heavy-ion collisions are briefly reviewed.
Stephanov Mikhail
doaj +1 more source