Results 101 to 110 of about 11,033,430 (362)

Traffic Management in Residential Areas: Case Study the South District of Luxor City, Egypt

open access: yesARCHive-SR, 2019
Traffic management includes the implementation of a wide range of measures, devices and techniques based on a combination of parallel strategies, to improve safety and livability on streets by reducing the effect of vehicular traffic.
Riam Mohamed Elsagher Mahmod Elmorshedy
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

On the distribution of critical points of a polynomial [PDF]

open access: yesElectronic Communications in Probability, 2012
This paper proves that if points $Z_1,Z_2,...$ are chosen independently and identically using some measure $ $ from the unit circle in the complex plane, with $p_n(z) = (z-Z_1)(z-Z_2)...(z-Z_n)$, then the empirical distribution of the critical points of $p_n$ converges weakly to $ $.
openaire   +4 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis

open access: yesNutrients, 2015
Excessive accumulation of lipids can lead to lipotoxicity, cell dysfunction and alteration in metabolic pathways, both in adipose tissue and peripheral organs, like liver, heart, pancreas and muscle.
C. Saponaro   +3 more
semanticscholar   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Existence of periodic solutions for non-autonomous second-order Hamiltonian systems

open access: yesElectronic Journal of Differential Equations, 2013
The purpose of this paper is to study the existence of periodic solutions for a class of non-autonomous second order Hamiltonian systems. New results are obtained by using the least action principle and the minimax methods, without the so-called Ahmad-
Yue Wu, Tianqing An
doaj  

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Existence of infinitely many solutions for nonlinear Neumann problems with indefinite coefficients

open access: yesElectronic Journal of Differential Equations, 2014
We consider the nonlinear Neumann boundary-value problem $$\displaylines{ - \Delta u +u =a(x)| u | ^{p-2}u\quad \text{in }\Omega,\cr \frac{\partial u}{\partial \nu}=\lambda b(x)|u|^{q-2}u\quad \text{on } \partial\Omega, }$$ where $N\ge 3$ and ...
Daisuke Naimen
doaj  

Indications of a ferromagnetic quantum critical point in [Formula: see text]. [PDF]

open access: yesSci Rep, 2023
Holmes-Hewett WF   +6 more
europepmc   +1 more source

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