Results 111 to 120 of about 7,571,221 (346)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The phase transition of the first order in the critical region of the gas-liquid system

open access: yesCondensed Matter Physics, 2014
This is a summarising investigation of the events of the phase transition of the first order that occur in the critical region below the liquid-gas critical point.
I.R. Yukhnovskii
doaj   +1 more source

Continuous spectrum of a fourth order nonhomogeneous differential operators with variable exponent

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2013
In this article, we consider the nonlinear eigenvalue problem: $$\left\{ \begin{array}{ll} \Delta(|\Delta u|^{p_1(x)-2}\Delta u)+\Delta(|\Delta u|^{p_2(x)-2}\Delta u)=\lambda|u|^{q(x)-2}u,\ {\rm in}\ \Omega, & \\ u=\Delta u=0,\ {\rm on ...
Bin Ge, Qing-Mei Zhou
doaj   +1 more source

Indications of a ferromagnetic quantum critical point in [Formula: see text]. [PDF]

open access: yesSci Rep, 2023
Holmes-Hewett WF   +6 more
europepmc   +1 more source

Quantum Critical Points-Experiments

open access: yes, 1998
We review experiments on Li(Ho,Tb)pY1-pF4 which test ideas about quantum critical phenomena in the clean (ferromagnetic) and disordered (spin glass) limits. The outstanding problem of the ‘anti-glass’ discovered for p=0.045 is also described. Finally, we point out the ubiquity of quantum critical points in condensed matter physics.
Aeppli, G., Rosenbaum, T. F.
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Existence of infinitely many periodic subharmonic solutions for nonlinear non-autonomous neutral differential equations

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we study the existence of an infinite number of subharmonic periodic solutions to a class of second-order neutral nonlinear functional differential equations.
Xiao-Bao Shu, Yongzeng Lai, Fei Xu
doaj  

Symmetry & Critical Points

open access: yes
Critical points of an invariant function may or may not be symmetric. We prove, however, that if a symmetric critical point exists, those adjacent to it are generically symmetry breaking. This mathematical mechanism is shown to carry important implications for our ability to efficiently minimize invariant nonconvex functions, in particular those ...
openaire   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Existence of solutions to fractional Hamiltonian systems with combined nonlinearities

open access: yesElectronic Journal of Differential Equations, 2016
This article concerns the existence of solutions for the fractional Hamiltonian system $$\displaylines{ - _tD^{\alpha}_{\infty}\big(_{-\infty}D^{\alpha}_{t}u(t)\big) -L(t)u(t)+\nabla W(t,u(t))=0,\cr u\in H^{\alpha}(\mathbb{R},\mathbb{R}^n ...
Ziheng Zhang, Rong Yuan
doaj  

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