The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
A critical point in chiral chromatography-mass spectrometry analysis of ketamine metabolites. [PDF]
Barbarossa A +3 more
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Superlinear fractional boundary value problems without the Ambrosetti-Rabinowitz condition
In this article, by means of a direct variational approach and the theory of the fractional differential space, we prove the existence of a nontrivial solution for superlinear fractional boundary value problems without Ambrosetti and Rabinowitz ...
Bin Ge +3 more
doaj
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Comparison of temperature and doping dependence of elastoresistivity near a putative nematic quantum critical point. [PDF]
Palmstrom JC +6 more
europepmc +1 more source
Critical point-based wireless sensors enabling tiny perturbation detection. [PDF]
Ma C +13 more
europepmc +1 more source
Critical Points of a Map to a Circle [PDF]
openaire +3 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Disclosing the True Critical Point of Fluids Confined in Nanopores. [PDF]
Owusu-Banahene EK +3 more
europepmc +1 more source

